Ergun Erdem, Maár Noémi, Radner Wolfgang, Barbazetto Irene, Schmidt-Erfurth Ursula, Stur Michael
Department of Ophthalmology, University of Vienna Medical School, Vienna, Austria.
Ophthalmology. 2003 Jan;110(1):65-9. doi: 10.1016/s0161-6420(02)01566-x.
To investigate the correlation between reading speed and scotoma size in patients with subfoveal occult with no classic choroidal neovascularization (CNV) in age-related macular degeneration (AMD) participating at 2 of 28 centers in the Verteporfin in Photodynamic Therapy trial.
Prospective, observational case series.
Twenty-two eyes of 22 patients with occult with no classic CNV in AMD.
Patients' reading speed was examined using a German-language reading test (Radner Lesetest). Scotoma size was measured using the microperimetry program 2.01 of the Rodenstock Scanning Laser Ophthalmoscope.
Reading acuity, reading speed, size of absolute (AS) and relative scotoma (RS).
There was a significant correlation between the size of AS and reading speed (r = -0.48, P = 0.023), as well as AS and reading acuity (r = 0.52, P = 0.013). No correlation was seen between RS and reading speed or reading capacity.
The size of absolute scotoma correlated significantly with reading capacity and reading speed and may influence these measures.
在光动力疗法试验中28个中心的2个中心参与研究的年龄相关性黄斑变性（AMD）患者中，研究中心凹下隐匿性无典型脉络膜新生血管（CNV）患者的阅读速度与暗点大小之间的相关性。
前瞻性观察性病例系列。
22例AMD隐匿性无典型CNV患者的22只眼。
使用德语阅读测试（拉德纳阅读测试）检查患者的阅读速度。使用罗登斯托克扫描激光检眼镜的微视野计程序2.01测量暗点大小。
阅读视力、阅读速度、绝对暗点（AS）和相对暗点（RS）的大小。
AS大小与阅读速度之间存在显著相关性（r = -0.48，P = 0.023），AS与阅读视力之间也存在显著相关性（r = 0.52，P = 0.013）。未发现RS与阅读速度或阅读能力之间存在相关性。
绝对暗点大小与阅读能力和阅读速度显著相关，可能会影响这些指标。
