Górecka R, Sitarska E, Kluciński W
Department of Clinical Sciences, Faculty of Veterinary Medicine, Warsaw Agricultural University, Grochowska 272, 03-849 Warsaw, Poland.
Pol J Vet Sci. 2002;5(4):209-16.
Antioxidant defences interact to form an integrated system. There is no comprehensive and uniform view on issues concerning the antioxidant status in horses. Therefore, the aim of the present study was to estimate antioxidant parameters in horses of different age, sex and breed as well as environment and relationship between different antioxidants. Parameters of selected antioxidants including superoxide dismutase (SOD), glutathione peroxidase (GSH-px), total antioxidant status (TAS), ceruloplasmin (CP), bilirubin, uric acid, zinc, copper and selenium were determined in blood of 80 clinically healthy horses. Antioxidant parameters significantly varied between horses form different environments or different breed and sex. Age of horses had no significant effect on antioxidant parameters. Significant correlation coefficients were observed between enzymatic and nonenzimatic antioxidants. The nature of the relationship between the antioxidant system in horses with respect to environmental factors is rather complex and to date only a part of system is known.
抗氧化防御相互作用形成一个综合系统。关于马匹抗氧化状态的问题，目前尚无全面统一的观点。因此，本研究的目的是评估不同年龄、性别、品种以及环境的马匹的抗氧化参数，以及不同抗氧化剂之间的关系。在80匹临床健康马匹的血液中测定了所选抗氧化剂的参数，包括超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-px）、总抗氧化状态（TAS）、铜蓝蛋白（CP）、胆红素、尿酸、锌、铜和硒。不同环境、品种和性别的马匹之间，抗氧化参数存在显著差异。马匹的年龄对抗氧化参数无显著影响。酶促抗氧化剂和非酶促抗氧化剂之间观察到显著的相关系数。马匹抗氧化系统与环境因素之间关系的本质相当复杂，迄今为止仅了解该系统的一部分。
