Freed D L, Banks A J, Longson D, Burley D M
Br Med J. 1975 May 31;2(5969):471-3. doi: 10.1136/bmj.2.5969.471.
Thirteen experienced male weightlifters taking high-protein diets and regular exercise took part in a double-blind crossover trial of methandienone 10 or 25 mg/day to seeif the drug improved athletic performance. Their improvemments were significantly greater on methandienone than on placebo; their body weights rose (though this seemed to be associated with water retention); and systolic blood pressure rose significantly. Methandienone caused many side effects, and three men had to withdraw because of them. All side effects disappeared after the drug was stopped. Anabolic steroids are effective only when given combination with exercise and high-protein diet. We deprecate their use in athletics but can suggest no way of stopping it.
13名有经验的男性举重运动员,他们采用高蛋白饮食并定期锻炼,参与了一项关于每天服用10毫克或25毫克美雄酮的双盲交叉试验,以观察该药物是否能提高运动表现。他们在服用美雄酮时的改善明显大于服用安慰剂时;他们的体重增加了(尽管这似乎与水分潴留有关);收缩压也显著升高。美雄酮引起了许多副作用,有3名男性因这些副作用而不得不退出试验。停药后所有副作用都消失了。合成代谢类固醇只有在与运动和高蛋白饮食相结合时才有效。我们不赞成在体育运动中使用它们,但却无法提出阻止其使用的办法。