利比亚班加西儿童（0至14岁）1型糖尿病的发病率（1991 - 2000年）

Incidence of type 1 diabetes in children (0-14 years) in Benghazi Libya (1991-2000).

作者信息

Kadiki O A, Roaeid R B M

机构信息

Benghazi Diabetes Centre, Benghazi, Libya.

出版信息

Diabetes Metab. 2002 Dec;28(6 Pt 1):463-7.

PMID:12522326

Abstract

BACKGROUND

Incidence of Type 1 diabetes in 0-14 year olds in Benghazi (Libya) during the period 1981-1990 was 7.0/10 5. The aim of this study is to report the incidence of Type 1 diabetes in 0-14 year olds in Benghazi Libya during the period 1991-2000.

METHODS

Incidence data are based on prospective registration of Type 1 diabetes new cases for the period 1991-2000 in Type 1 register.

RESULTS

A total of 276 (males 117, females 159) Type 1 diabetes new cases 0-14 years of age were identified during the period 1.01.1991-31.12.2000. Completeness of ascertainment was 100%. The average annual incidence per year was 7.8/100,000 population (95% CI 6.91-8.78). The standardized incidence rate (World standard) was 8.3/100,000 (95% CI 7.36-9.35). There was excess risk for females (9.1 95% CI 7.77-10.65) versus males (6.6 95% CI 5.45-7.89) (p<0.001). No significant temporal trend was observed, yet there was an increase in incidence rate over that reported for the period 1981-1990 (7.8 vs 7.0). Seasonal variation in incidence was significant.

CONCLUSION

It was concluded that the incidence of Type 1 diabetes in Benghazi is in the middle of the worldwide range close to the incidence in Mediterranean countries.

摘要

背景

1981 - 1990年期间，利比亚班加西0 - 14岁儿童1型糖尿病的发病率为7.0/10万。本研究旨在报告1991 - 2000年期间利比亚班加西0 - 14岁儿童1型糖尿病的发病率。

方法

发病率数据基于1991 - 2000年期间1型糖尿病新病例在1型登记处的前瞻性登记。

结果

在1991年1月1日至2000年12月31日期间，共确诊276例（男性117例，女性159例）0 - 14岁的1型糖尿病新病例。确诊的完整性为100%。每年的平均发病率为7.8/10万人口（95%可信区间6.91 - 8.78）。标准化发病率（世界标准）为8.3/10万（95%可信区间7.36 - 9.35）。女性（9.1，95%可信区间7.77 - 10.65）的发病风险高于男性（6.6，95%可信区间5.45 - 7.89）（p<0.001）。未观察到明显的时间趋势，但发病率较1981 - 1990年期间报告的有所增加（7.8对7.0）。发病率存在显著的季节性变化。