Elmehdawi Rafik R, Ehmida Mohammad, Elmagrehi Hanan, Alaysh Ahmad
Assistant Professor, Medical Department, Faculty of Medicine-Benghazi University, Libya.
Oman Med J. 2013 May;28(3):178-83. doi: 10.5001/omj.2013.50.
The aim of this study was to estimate the incidence of diabetic ketoacidosis and the mortality rate at Benghazi city.
A cross-sectional study of the records of all patients admitted with diabetic ketoacidosis to all Benghazi hospitals (governmental and private) between 1st of January and 31st of December 2007.
The annual incidence of diabetic ketoacidosis was 41.7 episodes/100,000 populations with a mean age of 33±20.1 years (2-93). Around 52% of all the episodes occurred in males and 2.6% of adult Diabetic ketoacidosis occurred in pregnant females. Type-2 diabetics were responsible for 27.7% of all episodes. The commonest precipitating factor in the whole study group was dose disruption (35%), followed by infection (20%). The most common presenting symptoms were gastrointestinal, whilst 3.5% of the patients were comatose at presentation. The overall mortality was 11.7% and there was no significant difference in mortality between males and females (11% vs. 12.6%; p=0.6); however, type-2 diabetics showed a significantly higher mortality rate (29.3% vs. 4.9%; p=0.000).
Diabetic ketoacidosis is a common condition in Libya with a high mortality rate and type-2 diabetics constitute a considerable number of the cases.
本研究旨在估算班加西市糖尿病酮症酸中毒的发病率及死亡率。
对2007年1月1日至12月31日期间所有入住班加西各医院（公立和私立）的糖尿病酮症酸中毒患者的记录进行横断面研究。
糖尿病酮症酸中毒的年发病率为41.7例/100,000人口，平均年龄为33±20.1岁（2 - 93岁）。所有病例中约52%发生在男性，2.6%的成年糖尿病酮症酸中毒发生在孕妇。2型糖尿病患者占所有病例的27.7%。整个研究组中最常见的诱发因素是剂量中断（35%），其次是感染（20%）。最常见的首发症状是胃肠道症状，3.5%的患者就诊时昏迷。总体死亡率为11.7%，男性和女性之间的死亡率无显著差异（11%对12.6%；p = 0.6）；然而，2型糖尿病患者的死亡率显著更高（29.3%对4.9%；p = 0.000）。
糖尿病酮症酸中毒在利比亚是一种常见疾病，死亡率高，2型糖尿病患者占相当比例的病例。
