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[香港市场零售的补肾阳中药天雄(附子)的药理学研究]

[Pharmacological study on Tianxiong (tuber of Aconitum carmichaeli Debx.), a Chinese drug for reinforcing the kidney yang retail in Hong Kong market].

作者信息

Cao H, Wang S T, Wu L Y, Wang X T, Jiang A P

机构信息

Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2001 Jun;26(6):369-72.

Abstract

OBJECTIVE

To explore the pharmacodynamic mechanism of Tianxiong (Aconitum carmichaeli) in tonifying the kidney and supporting Yang, so as to provide evidences for further development of new drugs treating Yang-eficiency of the kidney.

METHOD

Observing parameters such as visceral index, survival time of low-temperature swimming for hydrocortisone-induced Yang-deficiency model mouse and testis-removed kidney-deficiency model rat.

RESULT

The decoction of processed Tianxiong could strengthen the antifatigual ability and prolong the survival time of low-temperature swimming for mice, and promote immunization in rats.

CONCLUSION

Tianxiong is able to reinforce the kidney Yang, which reconforms the conclusion of "replenishing the fire of vital gate and the Qi of kidney" recorded in Chinese historical literature and proved by overseas clinical practice.

摘要

目的

探讨天雄(附子)补肾壮阳的药效机制,为进一步研发治疗肾阳虚新药提供依据。

方法

观察氢化可的松致肾阳虚模型小鼠的脏器指数、低温游泳存活时间及去睾肾虚模型大鼠的相关指标。

结果

制天雄水煎液能增强小鼠抗疲劳能力,延长其低温游泳存活时间,并能促进大鼠免疫功能。

结论

天雄具有补肾阳作用,这与中医古籍记载及国外临床实践验证的“补命门之火,益肾脏之气”的结论相符。

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