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[香港市场上乌头及相关草药(乌头属植物的根)及其炮制产品中乌头碱的测定]

[Determination of aconitine in wutou and related herbal drugs (roots of Aconitum) and their processed products in Hong Kong market].

作者信息

Cao H

机构信息

Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.

出版信息

Zhongguo Zhong Yao Za Zhi. 1993 May;18(5):279-81, 318.

PMID:8216801
Abstract

This paper deals with the determination of the poisonous aconitine-type alkaloids in roots of Aconitum in Hong Kong market by TLC scanning. The results show that the content of aconitine was 0.0041%-0.021% in processed roots of Aconitum carmichaeli, 0.0084%-0.034% in processed roots of A. kusnezoffii; 0.0012% and 0.0007% in crude and roasted lateral tuber of A. carmichaeli. Aconitine was not found in the processed product of Fuzi.

摘要

本文采用薄层扫描法对香港市场上乌头属植物根中的有毒乌头碱型生物碱进行测定。结果表明,制川乌根中乌头碱含量为0.0041% - 0.021%,制草乌根中乌头碱含量为0.0084% - 0.034%;川乌生侧根和炮制品中乌头碱含量分别为0.0012%和0.0007%。附子炮制品中未检出乌头碱。

相似文献

1
[Determination of aconitine in wutou and related herbal drugs (roots of Aconitum) and their processed products in Hong Kong market].[香港市场上乌头及相关草药(乌头属植物的根)及其炮制产品中乌头碱的测定]
Zhongguo Zhong Yao Za Zhi. 1993 May;18(5):279-81, 318.
2
[Separation and determination of the poisonous alkaloids in Aconitum kusnezoffii and its processed products].[草乌及其炮制品中有毒生物碱的分离与测定]
Zhong Yao Tong Bao. 1987 Feb;12(2):19-22.
3
Determination of aconitine-type alkaloids as markers in fuzi (Aconitum carmichaeli) by LC/(+)ESI/MS(3).采用液相色谱/(+)电喷雾电离串联质谱法(LC/(+)ESI/MS(3))测定附子(乌头)中乌头碱型生物碱作为标志物。
J Pharm Biomed Anal. 2008 Dec 1;48(4):1105-11. doi: 10.1016/j.jpba.2008.08.022. Epub 2008 Aug 28.
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Alkaloid profiling of the Chinese herbal medicine Fuzi by combination of matrix-assisted laser desorption ionization mass spectrometry with liquid chromatography-mass spectrometry.采用基质辅助激光解吸电离质谱联用液相色谱-质谱法对中药附子进行生物碱分析。
J Chromatogr A. 2009 Mar 13;1216(11):2169-78. doi: 10.1016/j.chroma.2008.11.077. Epub 2008 Dec 3.
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[Quantitative determination of total alkaloids and aconitine in the root of Aconitum carmichaeli and Aconitum kusnezoffii].[乌头和北乌头根中总生物碱及乌头碱的定量测定]
Zhong Yao Tong Bao. 1984 May;9(3):125-7.
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Qualitative and quantitative analysis of aconitine-type and lipo-alkaloids of Aconitum carmichaelii roots.乌头根中乌头碱型和脂类生物碱的定性与定量分析
J Chromatogr A. 2009 Mar 13;1216(11):2079-86. doi: 10.1016/j.chroma.2008.10.082. Epub 2008 Oct 28.
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[Determination of three kind of diester diterpenoid alkaloids (DDAs) in Aconitum carmichaeli and its processed products by HPLC].[高效液相色谱法测定附子及其炮制品中3种二酯型二萜生物碱(DDAs)]
Zhongguo Zhong Yao Za Zhi. 2006 Jul;31(14):1160-2.
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[The analysis of radix aconiti kusnezoffii by FT-Raman spectra].[草乌的傅里叶变换拉曼光谱分析]
Guang Pu Xue Yu Guang Pu Fen Xi. 2002 Jun;22(3):417-8.
9
Studies on the aconitine-type alkaloids in the roots of Aconitum Carmichaeli Debx. by HPLC/ESIMS/MS(n).用高效液相色谱/电喷雾离子化质谱/质谱法(n)对乌头根中乌头碱型生物碱的研究。
Talanta. 2009 Mar 15;77(5):1800-7. doi: 10.1016/j.talanta.2008.10.022. Epub 2008 Oct 22.
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Metabolomics study on Fuzi and its processed products using ultra-performance liquid-chromatography/electrospray-ionization synapt high-definition mass spectrometry coupled with pattern recognition analysis.基于超高效液相色谱/电喷雾电离串联高分辨率质谱联用技术与模式识别分析的附子及其炮制品代谢组学研究。
Analyst. 2012 Jan 7;137(1):170-85. doi: 10.1039/c1an15833c. Epub 2011 Oct 26.

引用本文的文献

1
A comparative study on the traditional Indian Shodhana and Chinese processing methods for aconite roots by characterization and determination of the major components.通过对主要成分的表征和测定,对印度传统的附子净化方法与中国的炮制方法进行比较研究。
Chem Cent J. 2013 Oct 25;7(1):169. doi: 10.1186/1752-153X-7-169.
2
Incidence of herb-induced aconitine poisoning in Hong Kong: impact of publicity measures to promote awareness among the herbalists and the public.香港草药引起乌头碱中毒的发生率:宣传措施对提高中医师及公众认知的影响。
Drug Saf. 2002;25(11):823-8. doi: 10.2165/00002018-200225110-00006.