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威廉·贝特森:一位超越时代的生物学家。

William Bateson: a biologist ahead of his time.

作者信息

Bateson Patrick

机构信息

Sub-Department of Animal Behaviour, University of Cambridge, Madingley, UK.

出版信息

J Genet. 2002 Aug;81(2):49-58. doi: 10.1007/BF02715900.

Abstract

William Bateson coined the term genetics and, more than anybody else, championed the principles of heredity discovered by Gregor Mendel. Nevertheless, his reputation is soured by the positions he took about the discontinuities in inheritance that might precede formation of a new species and by his reluctance to accept, in its full-blooded form, the view of chromosomes as the controllers of individual development. Growing evidence suggests that both of these positions have been vindicated. New species are now thought to arise as the result of genetic interactions, chromosomal rearrangements, or both, that render hybrids less viable or sterile. Chromosomes are the sites of genes but genes move between chromosomes much more readily than had been previously believed and chromosomes are not causal in individual development. Development, like speciation, requires an understanding of the interactions between genes and the interplay between the individual and its environment.

摘要

威廉·贝特森创造了“遗传学”这个术语,并且比其他任何人都更支持格雷戈尔·孟德尔所发现的遗传原理。然而,他的声誉因他对新物种形成之前遗传不连续性的立场以及他不愿完全接受染色体是个体发育控制者的观点而受损。越来越多的证据表明,这两种立场都已得到证实。现在认为新物种的出现是基因相互作用、染色体重排或两者兼而有之的结果,这些会使杂种的生存能力或繁殖能力降低。染色体是基因的所在位置,但基因在染色体之间移动的容易程度比以前认为的要高得多,而且染色体在个体发育中并非起因果作用。发育与物种形成一样,需要理解基因之间的相互作用以及个体与其环境之间的相互影响。

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