Department of Pediatrics, Hunterdon Medical Center, Flemington, NJ, USA.
Ann Sci. 2022 Oct;79(4):468-496. doi: 10.1080/00033790.2022.2113141. Epub 2022 Aug 17.
Early in the 20th century Bateson, Doncaster and Punnett formed a cooperative collective to share research findings on the chromosome theory of heredity (CTH). They cross-bred plants and animals to correlate behaviour of chromosomes and heredity of individual traits. Doncaster was the most enthusiastic proponent of the new theory and worked for years to convince Bateson and Punnett on its relevance to their own research. The two younger biologists collaborated with Bateson, the preeminent geneticist in England. As their own reputations developed, their research findings allied with the consensus on the importance of the CTH by the broader scientific community. After Doncaster's tragic death in 1920, major objections to the theory had been resolved; Bateson and Punnett then utilized the CTH to construct chromosome maps detailing locations of specific genes on particular chromosomes in several different species. The marriage of heredity and cytology enhanced confidence that the theory was an accurate mechanism to explain inheritance in both plants and animals.
20 世纪早期，贝特森、唐卡斯特和彭尼特组成了一个合作集体，共同分享染色体遗传理论（CTH）的研究成果。他们通过杂交植物和动物来关联染色体的行为和个体特征的遗传。唐卡斯特是这个新理论最热心的支持者，多年来一直努力说服贝特森和彭尼特，让他们相信该理论与他们自己的研究有关。这两位年轻的生物学家与英国杰出的遗传学家贝特森合作。随着他们自己声誉的提高，他们的研究成果与更广泛的科学界对 CTH 重要性的共识一致。1920 年唐卡斯特悲惨去世后，该理论的主要反对意见得到了解决；贝特森和彭尼特随后利用 CTH 构建了染色体图谱，详细描述了几个不同物种中特定染色体上特定基因的位置。遗传与细胞学的结合增强了人们的信心，即该理论是一个准确的机制，可以解释动植物的遗传。
