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长脉冲Nd:YAG激光与脉冲染料激光治疗酒渣鼻相关鼻毛细血管扩张症的疗效比较。

Comparison of efficacy between long-pulsed Nd:YAG laser and pulsed dye laser to treat rosacea-associated nasal telangiectasia.

作者信息

Kwon Won Joo, Park Bok Won, Cho Eun Byul, Park Eun Joo, Kim Kwang Ho, Kim Kwang Joong

机构信息

a Department of Dermatology , Hallym University Sacred Heart Hospital , Anyang , Korea.

出版信息

J Cosmet Laser Ther. 2018 Oct;20(5):260-264. doi: 10.1080/14764172.2017.1418510. Epub 2018 Feb 1.

Abstract

BACKGROUND

Rosacea is characterized by erythema on face, especially erythema and linear telangiectasia on the nose. Currently, various vascular lasers are used for treatment, and among them, are long-pulsed Nd:YAG(LPNY) and pulsed dye laser (PDL).

OBJECTIVES

This study compared the efficacy of LPNY and PDL in treating rosacea-associated nasal telangiectasia.

METHODS

Patients with rosacea who showed erythema and telangiectasia on the nose were included. Each patient was treated with PDL on the left side of the nasal bridge, and LPNY on the right side, three times with 4-week intervals. At the end of the treatment, two independent dermatologists evaluated overall treatment response compared with baseline.

RESULTS

The physician's assessment of treatment concluded that good improvement was seen in six PDL and seven LPNY patients, and excellent improvement five PDL and four LPNY patients. There was no significant difference (p = 0.62, 95%CI) between the groups. Overall improvement was similar; however, LPNY induced a greater response in thick, dilated vessels, while erythema with mild telangiectasia was more responsive to PDL.

CONCLUSION

Both LPNY and PDL are effective in treating rosacea-associated nasal telangiectasia. If LPNY is used properly to avoid side effects with careful consideration, it can also be used as a good modality.

摘要

背景

酒渣鼻的特征是面部红斑,尤其是鼻部的红斑和线状毛细血管扩张。目前,各种血管激光用于治疗,其中包括长脉冲Nd:YAG(LPNY)和脉冲染料激光(PDL)。

目的

本研究比较了LPNY和PDL治疗酒渣鼻相关鼻部毛细血管扩张的疗效。

方法

纳入鼻部有红斑和毛细血管扩张的酒渣鼻患者。每位患者鼻梁左侧接受PDL治疗,右侧接受LPNY治疗,共3次,间隔4周。治疗结束时,两名独立的皮肤科医生评估总体治疗反应并与基线进行比较。

结果

医生对治疗的评估得出,6例接受PDL治疗和7例接受LPNY治疗的患者改善良好,5例接受PDL治疗和4例接受LPNY治疗的患者改善极佳。两组之间无显著差异(p = 0.62,95%CI)。总体改善情况相似;然而,LPNY对粗大、扩张的血管反应更大,而伴有轻度毛细血管扩张的红斑对PDL反应更敏感。

结论

LPNY和PDL治疗酒渣鼻相关鼻部毛细血管扩张均有效。如果正确使用LPNY并仔细考虑避免副作用,它也可作为一种良好的治疗方式。

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