Chedrawy Edgar G, Chiu Ray C J
Division of Cardiac Surgery, McGill University Health Center, Montreal, Quebec, Canada.
Artif Cells Blood Substit Immobil Biotechnol. 2002 Sep-Nov;30(5-6):517-32. doi: 10.1081/bio-120016352.
Cellular cardiomyoplasty (cell therapy for myocardial regeneration) targets the basic pathophysiology of heart failure, the irreversible loss of functional cardiomyocytes, and represents a novel means of augmenting cardiomyocyte number and contractile function of the failing heart. We discuss briefly the concept of myocardial regeneration and explore various cell types that may act as potential sources for myocardial tissue engineering.
细胞心肌成形术(用于心肌再生的细胞治疗)针对心力衰竭的基本病理生理学,即功能性心肌细胞的不可逆丧失,是增加衰竭心脏心肌细胞数量和收缩功能的一种新方法。我们简要讨论心肌再生的概念,并探索各种可能作为心肌组织工程潜在细胞来源的细胞类型。