Piano Mariann R, Carrigan Timothy M
Medical-Surgical Nursing, University of Illinois at Chicago, College of Nursing, Chicago, Ill 60612, USA.
J Cardiovasc Nurs. 2003 Nov-Dec;18(5):374-81. doi: 10.1097/00005082-200311000-00009.
One of the most promising new therapeutic techniques for the augmentation and regeneration of the myocardium is cellular cardiomyoplasty. Reports from animal and clinical investigations indicate that the transplant of different cell types, such as autologous skeletal myoblasts and adult stem cells, into injured myocardium results in the generation of new cardiac myocytes and improvement in myocardial performance. Although there is no consensus with regard to the best cell type to transplant or the extent of myocardial renewal and regeneration, the technique of cardiac cellular myoplasty may become one of the most important advancements in the treatment of cardiovascular diseases such as myocardial infarction and heart failure.
心肌增强与再生最有前景的新治疗技术之一是细胞心肌成形术。动物和临床研究报告表明，将不同类型的细胞，如自体骨骼肌成肌细胞和成人干细胞，移植到受损心肌中可导致新心肌细胞的生成并改善心肌功能。尽管对于最佳移植细胞类型或心肌更新与再生的程度尚无共识，但细胞心肌成形术可能成为治疗心肌梗死和心力衰竭等心血管疾病最重要的进展之一。
