前列腺素X（前列环素）的化学结构。
The chemical structure of prostaglandin X (prostacyclin).
作者信息
Whittaker N, Bunting S, Salmon J, Moncada S, Vane J R, Johnson R A, Morton D R, Kinner J H, Gorman R R, McGuire J C, Sun F F
出版信息
Prostaglandins. 1976 Dec;12(6):915-28. doi: 10.1016/0090-6980(76)90126-x.
The chemical structure of prostaglandin X, the anti-aggregatory substance derived from prostaglandin endoperoxides, is 9-deoxy-6, 6alpha-epoxy-delta5-PGF1alpha. The stable compound formed when prostaglandin X undergoes a chemical transformation in biological systems in 6-keto-PGF1alpha. Prostaglandin X is stabilized in aqueous preparations by raising the pH to 8.5 or higher. The trivial name prostacyclin is proposed for 9-deoxy-6, 9alpha-epoxy-delta5-PGF1alpha.
前列腺素X是一种由前列腺素内过氧化物衍生而来的抗聚集物质，其化学结构为9-脱氧-6,6α-环氧-Δ5-PGF1α。当前列腺素X在生物系统中发生化学转化时形成的稳定化合物是6-酮-PGF1α。通过将pH值提高到8.5或更高，前列腺素X在水性制剂中得以稳定。9-脱氧-6,9α-环氧-Δ5-PGF1α的俗名被提议为前列环素。
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