Wu H, Zhou X, Zhang P, Zhang J, Li X, Zhang W
College of Stomatology, West China University of Medical Sciences.
Hua Xi Kou Qiang Yi Xue Za Zhi. 1999 May;17(2):113-5.
To compare the influence of 6 caries-preventive agents containing fluoride and trace element on dental enamel decalcification and observe the relationship between enamel decalcification and time of early carious lesions.
84 bovine teeth were selected and divided into 7 groups. Experimental groups were treated with SrF, SnF2, (NH4)2 MoO2F4, ZnF, LaF and NaF with the same [F-]concentration and deionised water respectively, then all the specimens formed artificial carious lesion in lactic acid gel.
The [Ca2+] concentration of lactic acid gel showed a variety of enamel decalcification among specimens treated with fluoride agents after 48 hours, on the other hand, all the specimens presented a platform of enamel decalcification after 48 hours. SnF2 demonstrated the strongest inhibition on enamel decalcification, meanwhile, NaF has the minimum influence on it.
The time of forming artificial carious lesion with acid etch is about 48 hours, moreover, caries-preventive agents containing fluoride and trace element are effectively able to inhibit enamel decalcification, and the potential mechanism is the interaction of fluoride and trace element.
比较6种含氟及微量元素的防龋剂对牙釉质脱矿的影响,并观察釉质脱矿与早期龋损时间的关系。
选取84颗牛牙,分为7组。实验组分别用相同氟离子浓度的SrF、SnF2、(NH4)2MoO2F4、ZnF、LaF和NaF以及去离子水处理,然后所有标本在乳酸凝胶中形成人工龋损。
48小时后,用氟化物处理的标本中,乳酸凝胶的[Ca2+]浓度显示出各种牙釉质脱矿情况,另一方面,48小时后所有标本都呈现出牙釉质脱矿平台。SnF2对牙釉质脱矿的抑制作用最强,同时,NaF对其影响最小。
用酸蚀形成人工龋损的时间约为48小时,此外,含氟及微量元素的防龋剂能有效抑制牙釉质脱矿,其潜在机制是氟与微量元素的相互作用。