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本文引用的文献

1
Sexual activity in hypertensive men treated with valsartan or carvedilol: a crossover study.
Am J Hypertens. 2001 Jan;14(1):27-31. doi: 10.1016/s0895-7061(00)01214-0.
2
Erectile dysfunction in general medicine practice: prevalence and clinical correlates.
Int J Impot Res. 2000 Feb;12(1):41-5. doi: 10.1038/sj.ijir.3900457.
3
Erectile dysfunction.勃起功能障碍
N Engl J Med. 2000 Jun 15;342(24):1802-13. doi: 10.1056/NEJM200006153422407.
4
Nitric oxide and penile erection: is erectile dysfunction another manifestation of vascular disease?
Cardiovasc Res. 1999 Aug 15;43(3):658-65. doi: 10.1016/s0008-6363(99)00135-2.
5
Sexual function in men with diabetes type 2: association with glycemic control.2型糖尿病男性的性功能:与血糖控制的关联
J Urol. 2000 Mar;163(3):788-91.
6
Incidence of erectile dysfunction in men 40 to 69 years old: longitudinal results from the Massachusetts male aging study.40至69岁男性勃起功能障碍的发病率:马萨诸塞州男性老龄化研究的纵向结果。
J Urol. 2000 Feb;163(2):460-3.
7
Impaired ascendant central pathways conduction in impotent diabetic subjects.
Acta Neurol Scand. 1999 Jun;99(6):381-6. doi: 10.1111/j.1600-0404.1999.tb07368.x.
8
Diagnostic evaluation of the erectile function domain of the International Index of Erectile Function.国际勃起功能指数勃起功能领域的诊断评估
Urology. 1999 Aug;54(2):346-51. doi: 10.1016/s0090-4295(99)00099-0.
9
Drug-related erectile dysfunction.药物相关性勃起功能障碍
Adverse Drug React Toxicol Rev. 1999 Mar;18(1):5-24.
10
Diabetes and vascular impotence: does insulin dependence increase the relative severity?糖尿病与血管性阳痿:胰岛素依赖是否会增加相对严重程度?
Int J Impot Res. 1999 Apr;11(2):87-9. doi: 10.1038/sj.ijir.3900387.

糖尿病、高血压或两种疾病并存男性勃起功能障碍的患病率及危险因素:对1412名以色列男性的社区调查

Prevalence and risk factors for erectile dysfunction in men with diabetes, hypertension, or both diseases: a community survey among 1,412 Israeli men.

作者信息

Roth Arie, Kalter-Leibovici Ofra, Kerbis Yehuda, Tenenbaum-Koren Ella, Chen Juza, Sobol Tamar, Raz Itamar

机构信息

Department of Cardiology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.

出版信息

Clin Cardiol. 2003 Jan;26(1):25-30. doi: 10.1002/clc.4960260106.

DOI:10.1002/clc.4960260106
PMID:12539809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6654434/
Abstract

BACKGROUND

Erectile dysfunction (ED) and cardiovascular disease share common risk factors and may be further aggravated by medical treatment for reducing them.

HYPOTHESIS

The study was undertaken to assess the prevalence of ED in patients with diabetes (DM), hypertension (HTN), or both diseases, and to evaluate the effect of patient age, medical treatment, and disease duration and control on the prevalence of ED in this population.

METHODS

A group of 150 primary practitioners who had patients with known DM and/or HTN conducted a survey, utilizing IIEF-15, a 15-item multidimensional, self-administered questionnaire used for the clinical assessment of ED.

RESULTS

In all, 1,412 patients were included: 37% had DM, 38% had HTN, and 25% had both diseases. Their mean age was 55, 58, and 60 years, and 62, 46, and 67% had some degree of ED, respectively. The prevalence of ED increased with age and disease duration in each age group and was higher in subjects with DM than in those with HTN, especially in those aged < 65 years. Poor glycemic control was associated with a higher prevalence rate of ED early in the course of the disease. There was no significant difference in the prevalence of ED according to type and number of antihypertensive drugs.

CONCLUSIONS

Erectile dysfunction is common among patients at high risk for cardiovascular disease because of diabetes and/or HTN. Diabetic men are affected earlier than those with HTN. Given the high frequency of ED in young patients with these risk factors, physicians should encourage an open discussion on the subject during routine visits to promote early detection and treatment.

摘要

背景

勃起功能障碍(ED)与心血管疾病有共同的危险因素,且用于降低这些危险因素的医学治疗可能会使其进一步加重。

假设

本研究旨在评估糖尿病(DM)、高血压(HTN)或两种疾病并存患者中ED的患病率,并评估患者年龄、医学治疗、疾病持续时间及控制情况对该人群ED患病率的影响。

方法

一组拥有已知DM和/或HTN患者的150名初级从业者进行了一项调查,使用国际勃起功能指数-15(IIEF-15),这是一份用于ED临床评估的15项多维自填问卷。

结果

总共纳入了1412名患者:37%患有DM,38%患有HTN,25%患有两种疾病。他们的平均年龄分别为55岁、58岁和60岁,ED发生率分别为62%、46%和67%。在每个年龄组中,ED患病率均随年龄和疾病持续时间的增加而升高,DM患者的ED患病率高于HTN患者,尤其是在年龄<65岁的人群中。血糖控制不佳与疾病早期较高的ED患病率相关。根据抗高血压药物的类型和数量,ED患病率无显著差异。

结论

由于糖尿病和/或HTN,勃起功能障碍在心血管疾病高危患者中很常见。糖尿病男性比高血压男性更早受到影响。鉴于有这些危险因素的年轻患者中ED发生率较高,医生应在常规就诊时鼓励就该主题进行公开讨论,以促进早期发现和治疗。