Taiwo Babafemi O, Hicks Charles B
Early Intervention Clinic, Lincoln Health Center, Durham, NC 27707, USA.
South Med J. 2002 Nov;95(11):1312-7.
The term "primary HIV infection" refers to the period from initial infection with the human immunodeficiency virus to complete seroconversion. It is a period of extreme infectiousness. The occurrence and severity of symptoms during primary HIV infection correlate with the rapidity of clinical and immunologic decline. Treatment of patients during primary infection may improve immune preservation and reconstitution. In this review article, we present information that will help clinicians understand, recognize, and diagnose primary HIV infection. The current approach to management of primary HIV infection is based more on expert opinion than clinical trial results, though ongoing clinical trials should provide more information about this syndrome.
“原发性HIV感染”一词指从初次感染人类免疫缺陷病毒到完全血清转化的时期。这是一个极具传染性的时期。原发性HIV感染期间症状的出现和严重程度与临床和免疫功能下降的速度相关。原发性感染期间对患者进行治疗可能会改善免疫保护和重建。在这篇综述文章中,我们提供的信息将有助于临床医生理解、识别和诊断原发性HIV感染。目前对原发性HIV感染的管理方法更多基于专家意见而非临床试验结果,不过正在进行的临床试验应该会提供更多关于这一综合征的信息。