Olby Robert
Department of the History and Philosophy of Science, 1017 Cathedral of Learning, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA. olbyr+@pitt.edu
Nature. 2003 Jan 23;421(6921):402-5. doi: 10.1038/nature01397.
Past discoveries usually become aggrandized in retrospect, especially at jubilee celebrations, and the double helix is no exception. The historical record reveals a muted response by the scientific community to the proposal of this structure in 1953. Indeed, it was only when the outlines appeared of a mechanism for DNA's involvement in protein synthesis that the biochemical community began to take a serious interest in the structure.
过去的发现通常在回顾时会被夸大,尤其是在周年庆典上,双螺旋结构也不例外。历史记录显示,1953年科学界对这一结构的提议反应平淡。事实上,直到出现了DNA参与蛋白质合成的机制轮廓时,生物化学界才开始认真关注这一结构。