McPhail Kerry L, Gerwick William H
College of Pharmacy, Oregon State University, Corvallis, Oregon 97331, USA.
J Nat Prod. 2003 Jan;66(1):132-5. doi: 10.1021/np0204186.
Three new malyngamides, U (1), V (2), and W (3), all possessing an uncommon oxygenation pattern, have been isolated from the marine cyanobacterium Lyngbya majuscula collected in Papua New Guinea. The planar structures of these compounds were deduced from NMR data. Aspects of their relative stereochemistry were investigated using selective (1)H decoupling, 1D and 2D NOESY, and E-COSY experiments in three different NMR solvents.
从采集于巴布亚新几内亚的海洋蓝藻大鞘丝藻(Lyngbya majuscula)中分离出了三种新的马琳酰胺类化合物,U(1)、V(2)和W(3),它们都具有不常见的氧化模式。这些化合物的平面结构由核磁共振数据推导得出。使用选择性¹H去耦、一维和二维核Overhauser效应光谱(NOESY)以及在三种不同核磁共振溶剂中的E-COSY实验研究了它们相对立体化学的各个方面。