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维替泊芬光动力疗法治疗高度近视性黄斑中心凹下脉络膜新生血管

Verteporfin photodynamic therapy in highly myopic subfoveal choroidal neovascularisation.

作者信息

Montero J A, Ruiz-Moreno J M

机构信息

Instituto Oftalmológico de Alicante, Vitreo-Retinal Unit, Spain.

出版信息

Br J Ophthalmol. 2003 Feb;87(2):173-6. doi: 10.1136/bjo.87.2.173.

Abstract

AIMS

To analyse the visual and angiographic results of photodynamic therapy (PDT) with verteporfin in highly myopic patients with subfoveal choroidal neovascularisation (CNV).

METHODS

PDT was performed on highly myopic patients with subfoveal CNV. The patient population was divided into two groups according to age at onset of CNV (group 1 aged < or = 55 and group 2 aged >55 years old). Best corrected visual acuity (BCVA) and angiographic findings were considered.

RESULTS

At the end of follow up group 2 had worse BCVA than group 1. 76% of patients in both groups showed a complete closure of CNV at the end of follow up.

CONCLUSION

Visual prognosis of myopic CNV treated by PDT is influenced by age at onset.

摘要

目的

分析维替泊芬光动力疗法(PDT)治疗高度近视性黄斑下脉络膜新生血管(CNV)患者的视力及血管造影结果。

方法

对高度近视性黄斑下CNV患者进行PDT治疗。根据CNV发病年龄将患者人群分为两组(1组年龄≤55岁,2组年龄>55岁)。评估最佳矫正视力(BCVA)及血管造影结果。

结果

随访结束时,2组的BCVA比1组差。两组中76%的患者在随访结束时CNV完全闭合。

结论

PDT治疗近视性CNV的视力预后受发病年龄影响。

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