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高度近视患者黄斑下脉络膜新生血管的手术切除

Surgical removal of subfoveal choroidal neovascularisation in highly myopic patients.

作者信息

Ruiz-Moreno J M, de la Vega C

机构信息

Department of Ophthalmology, Miguel Hernández University School of Medicine, Alicante, Spain.

出版信息

Br J Ophthalmol. 2001 Sep;85(9):1041-3. doi: 10.1136/bjo.85.9.1041.

Abstract

AIM

To analyse the visual results obtained in the treatment of subretinal choroidal neovascularisation (CNV) in patients with high myopia by vitrectomy and extraction of the neovascular membrane.

METHODS

22 eyes of 22 patients with high myopia (>-6 dioptres and/or axial length >26 mm) with subfoveal CNV treated by extraction of the CNV were analysed retrospectively. The patients' mean age was 60.27 (SD 16.41) years (range 32-83 years). The mean follow up was 29.3 (9.9) months (range 12-42 months).

RESULTS

Best corrected visual acuity (BCVA) preoperatively was 0.09 (0.07) (range 0.01-0.3). After treatment BCVA was 0.12 (0.10) (range 0.01-0.4), a difference without statistical significance (p=0.03, Student's t test paired data). In four cases the CNV recurred, in three cases cataract developed that required extraction, and in one case retinal detachment occurred in the early postoperative period. Topical treatment was necessary in two cases to lower the intraocular pressure.

CONCLUSIONS

The treatment of subfoveal CNV in highly myopic patients by surgical removal by vitrectomy does not achieve any significant improvement of the BCVA.

摘要

目的

分析通过玻璃体切除术及取出新生血管膜治疗高度近视患者视网膜下脉络膜新生血管(CNV)所获得的视觉效果。

方法

回顾性分析22例高度近视(>-6屈光度和/或眼轴长度>26mm)且黄斑中心凹下CNV患者的22只眼,这些患者均接受了CNV取出术治疗。患者的平均年龄为60.27(标准差16.41)岁(范围32 - 83岁)。平均随访时间为29.3(9.9)个月(范围12 - 42个月)。

结果

术前最佳矫正视力(BCVA)为0.09(0.07)(范围0.01 - 0.3)。治疗后BCVA为0.12(0.10)(范围0.01 - 0.4),差异无统计学意义(p = 0.03,配对数据的学生t检验)。4例CNV复发,3例出现需要手术摘除的白内障,1例在术后早期发生视网膜脱离。2例需要局部治疗以降低眼压。

结论

通过玻璃体切除术手术切除高度近视患者黄斑中心凹下CNV并不能使BCVA得到显著改善。

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Arch Ophthalmol. 2000 Mar;118(3):344-50. doi: 10.1001/archopht.118.3.344.
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