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阿拉伯裔美国人中的糖尿病流行病学。

Epidemiology of diabetes among Arab Americans.

作者信息

Jaber Linda A, Brown Morton B, Hammad Adnan, Nowak Sandra N, Zhu Qian, Ghafoor Anisa, Herman William H

机构信息

Department of Pharmacy Practice, Wayne State University, Detroit, Michigan 48201, USA.

出版信息

Diabetes Care. 2003 Feb;26(2):308-13. doi: 10.2337/diacare.26.2.308.

Abstract

OBJECTIVE

To examine the prevalence of diabetes and glucose intolerance by age and sex in the Arab-American community of Dearborn, Michigan.

RESEARCH DESIGN AND METHODS

Participants were randomly selected adult Arab Americans, 20-75 years of age, from randomly selected households in Dearborn, Michigan. Demographic and anthropometric data were recorded. Glucose tolerance was assessed with 2-h 75-g oral glucose tolerance tests and classified according to 1997 American Diabetes Association and 1998 World Health Organization criteria.

RESULTS

A total of 626 eligible adults were selected, and 542 participated (87% response rate). Because prevalence increases with age and the overall response rate for women (328/352; 93%) was higher than that for men (214/274; 78%), prevalence rates were adjusted for age and sex. The overall prevalence of diabetes was 15.5% (95% CI 12.2-18.7%) in women and 20.1% (15.0-25.2%) in men (P = 0.13). The prevalence of previously diagnosed diabetes was similar to that of undiagnosed diabetes. Impaired glucose tolerance (IGT) and/or impaired fasting glucose (IFG) were present in 16.8% (12.8-20.8%) of women and 29.7% (23.4-35.9%) of men (P = 0.0007). The combined rates of glucose intolerance (diabetes, IGT, and IFG) were 32.3% (27.8-36.7%) for women and 49.8% (43.1-56.4%) for men (P < 0.0001). Among younger adults, the prevalence in men was higher than that in women. As expected, subjects with diabetes or IGT/IFG were older and had greater BMI and waist-to-hip ratios than subjects with normal glucose tolerance.

CONCLUSIONS

The prevalence of diabetes and glucose intolerance is extremely high among adult Arab Americans in Michigan and represents a major clinical and public health problem. Community-based intervention programs to prevent and treat diabetes are urgently needed.

摘要

目的

调查密歇根州迪尔伯恩阿拉伯裔美国人社区中糖尿病及糖耐量异常按年龄和性别的患病率。

研究设计与方法

参与者是从密歇根州迪尔伯恩随机抽取的家庭中随机选取的20至75岁成年阿拉伯裔美国人。记录人口统计学和人体测量学数据。采用2小时75克口服葡萄糖耐量试验评估糖耐量,并根据1997年美国糖尿病协会和1998年世界卫生组织的标准进行分类。

结果

共选取626名符合条件的成年人,542人参与(应答率87%)。由于患病率随年龄增长而升高,且女性的总体应答率(328/352;93%)高于男性(214/274;78%),因此对患病率进行了年龄和性别的调整。女性糖尿病总体患病率为15.5%(95%可信区间12.2 - 18.7%),男性为20.1%(15.0 - 25.2%)(P = 0.13)。既往诊断糖尿病的患病率与未诊断糖尿病的患病率相似。女性中糖耐量受损(IGT)和/或空腹血糖受损(IFG)的患病率为16.8%(12.8 - 20.8%),男性为29.7%(23.4 - 35.9%)(P = 0.0007)。糖耐量异常(糖尿病、IGT和IFG)的合并患病率女性为32.3%(27.8 - 36.7%),男性为49.8%(43.1 - 56.4%)(P < 0.0001)。在较年轻的成年人中,男性患病率高于女性。正如预期那样,糖尿病或IGT/IFG患者比糖耐量正常的患者年龄更大,体重指数和腰臀比更高。

结论

密歇根州成年阿拉伯裔美国人中糖尿病和糖耐量异常的患病率极高,是一个重大的临床和公共卫生问题。迫切需要开展基于社区的糖尿病预防和治疗干预项目

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