Rattanadilok Na Bhuket Tapanok, Sunakorn Pramuan, Suwanjutha Subharee, Nawanoparatkul Santi, Teeyapaiboonsilpa Pratueng
ARI Section, Department of Communicable Disease Control, Ministry of Public Health, Bangkok 10120, Thailand.
J Med Assoc Thai. 2002 Nov;85 Suppl 4:S1247-51.
Wheezing was detected in 251 of the 421 (59.6%) children under 5 years old suffering from acute lower respiratory infections (LRI) treated at the Takhli Hospital, Nakhon Sawan Province from November 1998 to October 2000. Bronchitis and pneumonia accounted for 55.0 per cent and 40.6 per cent of LRI with wheezing. Most of the patients, 162 of 251 (64.5%) cases were children under 2 years old. The wheezing symptom declined significantly in children older than 4 years of age. In this study, LRI with wheezing was found all year round but was more frequent in the rainy season similar to other respiratory infections. As the respiratory syncytial virus (RSV) infections were mainly found during the rainy season (July-October), the association of wheezing and RSV infections in the rainy season was evaluated. RSV causing LRI with wheezing in the rainy season revealed 54.7 per cent and 39.4 per cent in the first and second studied year, respectively. The two-year follow-up of 121 cases of LRI with wheezing showed that 37 cases (30.5%) had repeated episodes of wheezing. In conclusion, LRI with wheezing caused by RSV was commonly found in children under 2 years old. The occurrence was all the year round but predominantly in the rainy season.
1998年11月至2000年10月期间,在那空沙旺府塔克利医院接受治疗的421名5岁以下急性下呼吸道感染(LRI)儿童中,有251名(59.6%)被检测出有喘息症状。支气管炎和肺炎分别占伴有喘息的LRI的55.0%和40.6%。大多数患者,即251例中的162例(64.5%)为2岁以下儿童。喘息症状在4岁以上儿童中显著下降。在本研究中,伴有喘息的LRI全年都有发现,但与其他呼吸道感染一样,在雨季更为常见。由于呼吸道合胞病毒(RSV)感染主要在雨季(7月至10月)被发现,因此对雨季喘息与RSV感染之间的关联进行了评估。在研究的第一年和第二年,RSV导致雨季伴有喘息的LRI分别为54.7%和39.4%。对121例伴有喘息的LRI进行的两年随访显示,37例(30.5%)有反复喘息发作。总之,RSV引起的伴有喘息的LRI在2岁以下儿童中很常见。这种情况全年都有发生,但主要发生在雨季。