Dada Tanuj, Sudan Rajeev, Sinha Rajesh, Ray Manotosh, Sethi Harinder, Vajpayee Rasik B
Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
J Refract Surg. 2003 Jan-Feb;19(1):44-7. doi: 10.3928/1081-597X-20030101-09.
To evaluate the effectiveness, predictability, and safety of laser in situ keratomileusis (LASIK) for correcting myopia greater than -10.00 D.
Sixty-five eyes of 37 patients with myopia greater than -10.00 D underwent LASIK. Patients were evaluated on day 1, 1 week, 1, 3, and 6 months after surgery. Parameters evaluated were uncorrected visual acuity (UCVA) and best spectacle-corrected visual acuity (BSCVA), residual refractive error, regression of correction, and presence of any complication.
Mean preoperative BSCVA was 0.745 +/- 0.234, which improved to 0.8070 +/- 0.237 postoperatively. The average preoperative UCVA was 0.022 +/- 0.02; postoperative UCVA at 6 months was 0.536 +/- 0.255. UCVA of 20/40 or better was achieved in 58% (38 eyes) and 20/20 or better in 26% (17 eyes). The average refractive error before LASIK was -12.64 +/- 2.16 D (range -10.00 to -19.00 D). Mean residual refractive error 1 week following LASIK was -0.63 +/- 1.36 D, which regressed to a mean -1.78 +/- 2.08 D at the end of 6 months. Nineteen eyes (29%) were within +/-0.50 D of intended refractive correction.
LASIK was partially effective in the correction of high myopia. An initial overcorrection may be programmed to offset the effect of refractive regression.
评估准分子原位角膜磨镶术（LASIK）矫正近视度数大于-10.00D的有效性、可预测性及安全性。
37例近视度数大于-10.00D的患者的65只眼接受了LASIK手术。在术后第1天、1周、1、3和6个月对患者进行评估。评估参数包括裸眼视力（UCVA）、最佳矫正视力（BSCVA）、残余屈光不正、矫正度数回退以及是否存在任何并发症。
术前平均BSCVA为0.745±0.234，术后提高至0.8070±0.237。术前平均UCVA为0.022±0.02；术后6个月UCVA为0.536±0.255。58%（38只眼）的患者UCVA达到20/40或更好，26%（17只眼）达到20/20或更好。LASIK术前平均屈光不正为-12.64±2.16D（范围-10.00至-19.00D）。LASIK术后1周平均残余屈光不正为-0.63±1.36D，在6个月末回退至平均-1.78±2.08D。19只眼（29%）的屈光矫正度数在预期矫正度数的±0.50D范围内。
LASIK在矫正高度近视方面部分有效。可设定初始过度矫正以抵消屈光回退的影响。
