Yang C H, Srivastava P N
J Reprod Fertil. 1976 Mar;46(2):289-93. doi: 10.1530/jrf.0.0460289.
High concentrations of alpha-chlorohydrin were found to inhibit hyaluronidase, beta-glucuronidase, and aryl sulphatases in bull and rabbit spermatozoa, but not acrosin and neuraminidase. Preincubation of the enzyme and alpha-chlorohydrin was essential to achieve the maximum inhibition which was irreversible.
研究发现,高浓度的α-氯醇可抑制公牛和兔子精子中的透明质酸酶、β-葡萄糖醛酸酶和芳基硫酸酯酶,但对顶体酶和神经氨酸酶无抑制作用。酶与α-氯醇的预孵育对于实现不可逆的最大抑制作用至关重要。