Gambini Orsola, Campana Arturo, Garghentini Giacomo, Scarone Silvio
Psychiatric Branch, Department of Medicine, Surgery, and Dentistry, University of Milan Medical School, Italy.
J Neuropsychiatry Clin Neurosci. 2003 Winter;15(1):53-7. doi: 10.1176/jnp.15.1.53.
The authors obtained a frontal functions profile for 81 schizophrenic patients using six neuropsychological tests that evaluate the dorsolateral prefrontal cortex functions, i.e., working memory, executive functions, and strategic performance. They then analyzed the test performances with a cluster analysis, which produced a four-cluster solution. The results support the hypothesis that neuropsychological dysfunctions in schizophrenia are heterogeneous. The performances on many of the neuropsychological tests were also strongly correlated with verbal and nonverbal IQ, as measured by the Wechsler Adult Intelligence Scale-Revised.
作者使用六项评估背外侧前额叶皮质功能（即工作记忆、执行功能和策略性表现）的神经心理学测试，为81名精神分裂症患者获取了额叶功能概况。然后，他们用聚类分析对测试表现进行了分析，得出了一个四类解决方案。结果支持了精神分裂症患者神经心理功能障碍具有异质性这一假设。许多神经心理学测试的表现也与韦氏成人智力量表修订版所测量的言语和非言语智商密切相关。
