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邓金-哈特利豚鼠的自发性肿瘤

Spontaneous tumors in the Dunkin-Hartley guinea pig.

作者信息

Ediger R D, Kovatch R M

出版信息

J Natl Cancer Inst. 1976 Feb;56(2):293-4. doi: 10.1093/jnci/56.2.293.

DOI:10.1093/jnci/56.2.293
PMID:1255762
Abstract

Seventy-nine spontaneous neoplasms in Dunkin-Hartley guinea pigs were observed over a 9-year period in the Fort Detrick guinea pig colony. Sixty-three of the neoplasms were found during approximately 8,500 necropsies performed on animals under 27 months of age. The remaining 16 tumors were in 34 breeders maintained after 27 months of age on a natural life-span study. Of this group, 10 (29.4%) developed neoplasms by the termination of the study, when the animals were 80 months of age. The skin tumor, trichofolliculoma, of which there were 29, comprised the largest tumor classification.

摘要

在迪特里克堡豚鼠养殖基地的9年期间,观察到79例邓金-哈特利豚鼠自发性肿瘤。其中63例肿瘤是在对27月龄以下动物进行的约8500次尸检中发现的。其余16例肿瘤发生在34只27月龄后留作自然寿命研究的种豚鼠身上。在该组中,10只(29.4%)在研究结束时(动物80月龄时)发生了肿瘤。皮肤肿瘤毛囊瘤有29例,是数量最多的肿瘤类型。

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