N'-苯甲酰基-N-(叔丁基)苯甲酰肼的苯并杂环类似物的合成及杀虫活性：第2部分。苯并杂环部分苯环上取代基的引入。

Synthesis and insecticidal activity of benzoheterocyclic analogues of N'-benzoyl-N-(tert-butyl)benzohydrazide: Part 2. Introduction of substituents on the benzene rings of the benzoheterocycle moiety.

作者信息

Sawada Yoshihiro, Yanai Toshiaki, Nakagawa Harumi, Tsukamoto Yoshihisa, Yokoi Shinji, Yanagi Mikio, Toya Tetsuya, Sugizaki Hiroyasu, Kato Yasuhito, Shirakura Hidetoshi, Watanabe Tetsuo, Yajima Yoshimi, Kodama Seiichirou, Masui Akio

机构信息

Agroscience Research Laboratories, Sankyo Co Ltd, 1041, Yasu, Yasu-cho, Yasu-gun, Shiga-ken 520-2342, Japan.

出版信息

Pest Manag Sci. 2003 Jan;59(1):36-48. doi: 10.1002/ps.605.

DOI:10.1002/ps.605

PMID:12558098

Abstract

A series of N'-benzoheterocyclecarbonyl-N-tert-butyl-3,5-dimethylbenzohydrazide analogues possessing a variety of substituents on the benzene rings of the benzoheterocyle moieties were synthesized and tested for their insecticidal activity. The introduction of a methyl group at the R1 position of the benzoheterocycle moiety strongly increased the insecticidal activity. Among the analogues synthesized, N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-6-chromanecarbohydrazide showed the highest insecticidal activity (LC50 = 0.89 mg litre(-1)).

摘要

合成了一系列在苯并杂环部分的苯环上带有各种取代基的N'-苯并杂环羰基-N-叔丁基-3,5-二甲基苯甲酰肼类似物，并对其杀虫活性进行了测试。在苯并杂环部分的R1位置引入甲基显著提高了杀虫活性。在合成的类似物中，N'-叔丁基-N'-(3,5-二甲基苯甲酰基)-5-甲基-6-色满甲酰肼表现出最高的杀虫活性（LC50 = 0.89毫克/升）。