Montie J E, Straffon R A, Deodhar S D, Barna B
J Urol. 1976 Mar;115(3):239-42. doi: 10.1016/s0022-5347(17)59154-5.
We evaluated 25 patients with renal cell carcinoma for cell-mediated immunity using the microtoxicity assay. Normal controls frequently exhibited significant cell inhibition. The mean percentage cell inhibition in patients after nephrectomy was significantly higher than in patients before nephrectomy and significantly higher than normal male subjects. No other correlation was found with respect to the stage of the disease. The incidence of significant autoblocking activity was noted more commonly in patients after nephrectomy than in patients before nephrectomy.
我们使用微毒性试验评估了25例肾细胞癌患者的细胞介导免疫。正常对照组经常表现出显著的细胞抑制。肾切除术后患者的平均细胞抑制百分比显著高于肾切除术前患者,且显著高于正常男性受试者。未发现与疾病分期有其他相关性。肾切除术后患者中显著的自身阻断活性发生率比肾切除术前患者更常见。