Schölmerich J
Dept. of Internal Medicine I, University of Regensburg, Regensburg, Germany.
Endoscopy. 2003 Feb;35(2):164-70. doi: 10.1055/s-2003-37019.
Significant advances have been made in our understanding of the etiology of inflammatory bowel diseases, particularly with the identification of the first gene mutation associated with Crohn's disease; the treatment arsenal has also been expanded, and some new developments have been seen with regard to diagnosis as well. The importance of endoscopic features in relation to the prognosis has been extensively studied. New ultrasound techniques and magnetic resonance-based imaging are on the verge of modifying the diagnostic approach, particularly during follow-up in Crohn's disease of the small bowel. By contrast, virtual colonoscopy using computed tomography or magnetic resonance imaging does not appear to be of much help. However, the development of these new techniques is continuing rapidly, and an explosion of new information may be expected in the coming years.
我们对炎症性肠病病因的理解取得了重大进展,尤其是在鉴定出首个与克罗恩病相关的基因突变方面;治疗手段也有所扩展,诊断方面也有了一些新进展。内镜特征与预后的关系已得到广泛研究。新的超声技术和基于磁共振的成像即将改变诊断方法,特别是在小肠克罗恩病的随访期间。相比之下,使用计算机断层扫描或磁共振成像的虚拟结肠镜检查似乎帮助不大。然而,这些新技术正在迅速发展,预计未来几年将有大量新信息涌现。