Carter Jason R, Ray Chester A, Downs Emily M, Cooke William H
Department of Biomedical Engineering and Biological Sciences, Michigan Technological University, Houghton, Michigan 49931, USA.
J Appl Physiol (1985). 2003 Jun;94(6):2212-6. doi: 10.1152/japplphysiol.01109.2002. Epub 2003 Jan 31.
The effects of resistance training on arterial blood pressure and muscle sympathetic nerve activity (MSNA) at rest have not been established. Although endurance training is commonly recommended to lower arterial blood pressure, it is not known whether similar adaptations occur with resistance training. Therefore, we tested the hypothesis that whole body resistance training reduces arterial blood pressure at rest, with concomitant reductions in MSNA. Twelve young [21 +/- 0.3 (SE) yr] subjects underwent a program of whole body resistance training 3 days/wk for 8 wk. Resting arterial blood pressure (n = 12; automated sphygmomanometer) and MSNA (n = 8; peroneal nerve microneurography) were measured during a 5-min period of supine rest before and after exercise training. Thirteen additional young (21 +/- 0.8 yr) subjects served as controls. Resistance training significantly increased one-repetition maximum values in all trained muscle groups (P < 0.001), and it significantly decreased systolic (130 +/- 3 to 121 +/- 2 mmHg; P = 0.01), diastolic (69 +/- 3 to 61 +/- 2 mmHg; P = 0.04), and mean (89 +/- 2 to 81 +/- 2 mmHg; P = 0.01) arterial blood pressures at rest. Resistance training did not affect MSNA or heart rate. Arterial blood pressures and MSNA were unchanged, but heart rate increased after 8 wk of relative inactivity for subjects in the control group (61 +/- 2 to 67 +/- 3 beats/min; P = 0.01). These results indicate that whole body resistance exercise training might decrease the risk for development of cardiovascular disease by lowering arterial blood pressure but that reductions of pressure are not coupled to resistance exercise-induced decreases of sympathetic tone.
抗阻训练对静息时动脉血压和肌肉交感神经活动（MSNA）的影响尚未明确。尽管通常推荐耐力训练来降低动脉血压，但尚不清楚抗阻训练是否会产生类似的适应性变化。因此，我们检验了以下假设：全身抗阻训练可降低静息时的动脉血压，并伴随MSNA的降低。12名年轻受试者[21±0.3（标准误）岁]进行了为期8周、每周3天的全身抗阻训练计划。在运动训练前后的5分钟仰卧休息期间，测量静息动脉血压（n = 12；自动血压计）和MSNA（n = 8；腓总神经微神经ography）。另外13名年轻受试者（21±0.8岁）作为对照。抗阻训练显著提高了所有训练肌肉群的一次重复最大值（P < 0.001），并显著降低了静息时的收缩压（130±3至121±2 mmHg；P = 0.01）、舒张压（69±3至61±2 mmHg；P = 0.04）和平均动脉压（89±2至81±2 mmHg；P = 0.01）。抗阻训练不影响MSNA或心率。对照组受试者在8周相对不活动后，动脉血压和MSNA未改变，但心率增加（61±2至67±3次/分钟；P = 0.01）。这些结果表明，全身抗阻运动训练可能通过降低动脉血压来降低心血管疾病发生的风险，但血压的降低与抗阻运动引起的交感神经张力降低无关。
