Gróza S
Med Klin. 1976 Feb 27;71(9):378-9.
We investigated the serum prealbumin by the immuno-diffusion method quantitatively according to the method of Manzini in 20 normal persons, 30 patients with hepatitis virosa acuta, 24 patients with hepatitis chronica and 11 patients with cirrhosis of the liver. The serum prealbumin was significantly decreased in patients with hepatitis acuta virosa, hepatitis chronica aggressiva and in cirrhosis of the liver, but in the patients with the hepatitis chronica persistens the serum prealbumin levels were normal or little increased. According to our results we concluded that the determination of serum prealbumin is important only for the differential diagnosis between the hepatitis chronica aggressiva and hepatitis chronica persistens. However these determinations are not of values in the differential diagnosis between hepatitis chronica aggressiva and cirrhosis of the liver.
我们采用免疫扩散法,按照曼齐尼的方法,对20名正常人、30名急性病毒性肝炎患者、24名慢性肝炎患者和11名肝硬化患者的血清前白蛋白进行了定量研究。急性病毒性肝炎、侵袭性慢性肝炎和肝硬化患者的血清前白蛋白显著降低,但持续性慢性肝炎患者的血清前白蛋白水平正常或略有升高。根据我们的研究结果,我们得出结论,血清前白蛋白的测定仅对侵袭性慢性肝炎和持续性慢性肝炎的鉴别诊断具有重要意义。然而,这些测定在侵袭性慢性肝炎和肝硬化的鉴别诊断中并无价值。