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急性病毒性肝炎与重度活动期肝硬化的鉴别诊断(作者译)

[Differential diagnosis of acute viral hepatitis and liver cirrhosis with severe activity (author's transl)].

作者信息

Vido I, Rezai I

出版信息

Med Klin. 1975 Oct 3;70(40):1595-7.

PMID:52826
Abstract

Results of biochemical tests in 61 patients with acute viral hepatitis resp. 63 patients with subacute hepatitis were compared with laboratory findings of 27 patients with liver cirrhosis in the stage of severe activity of the disease. In acute and subacute viral hepatitis was the activity of GPT and CHE significantly higher than in active cirrhosis of the liver. In contrast to these findings was the activity of GLDH and the blood level of bilirubin in both groups of patients similar and for the differential diagnosis of no importance. Low albumin, high gammaglobulin and significant increase of IgG and IgA fractions of immunglobulins in serum are additionally to the results of the activity of some serum enzymes for the diagnosis of active liver cirrhosis in comparison to acute and subacute viral hepatitis of greatest value.

摘要

对61例急性病毒性肝炎患者以及63例亚急性肝炎患者的生化检测结果,与27例处于疾病严重活动期的肝硬化患者的实验室检查结果进行了比较。在急性和亚急性病毒性肝炎中,谷丙转氨酶(GPT)和胆碱酯酶(CHE)的活性显著高于活动性肝硬化。与这些结果相反,两组患者中谷氨酸脱氢酶(GLDH)的活性和胆红素血水平相似,对鉴别诊断无重要意义。与急性和亚急性病毒性肝炎相比,血清中低白蛋白、高球蛋白以及免疫球蛋白IgG和IgA组分的显著增加,对于诊断活动性肝硬化,除了一些血清酶活性结果外,具有最大价值。

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