Winthrop Kevin L, Steinberg Ellen B, Holmes Gary, Kainer Marion A, Werner S B, Winquist Andrea, Vugia Duc J
Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Am J Ophthalmol. 2003 Feb;135(2):223-4. doi: 10.1016/s0002-9394(02)01955-4.
To report national case-finding results for nontuberculous mycobacterial keratitis and describe its association with laser in situ keratomileusis (LASIK).
Enhanced passive disease reporting.
In April 2001, we investigated a California cluster of Mycobacterium chelonae keratitis associated with hyperopic LASIK using a contact lens mask. To identify other possibly related cases, the American Academy of Ophthalmology e-mailed its members asking them to report recent cases of nontuberculous mycobacterial keratitis to the Centers for Disease Control and Prevention.
Forty-three additional cases of keratitis were reported (onsets between August 2000 and June 2001). Of these, 31 occurred as part of two unrelated LASIK-associated outbreaks. The 12 other reported cases occurred in sporadic fashion. Of the latter cases, 4 were associated with LASIK surgery. None of the reported cases were related to the M. chelonae cluster in California.
Laser in situ keratomileusis-associated keratitis with nontuberculous mycobacteria may be more common than previously known.
报告非结核分枝杆菌性角膜炎的全国病例发现结果，并描述其与准分子原位角膜磨镶术（LASIK）的关联。
强化被动疾病报告。
2001年4月，我们使用隐形眼镜罩调查了加利福尼亚州一群与远视性LASIK相关的龟分枝杆菌性角膜炎病例。为了识别其他可能相关的病例，美国眼科学会向其成员发送电子邮件，要求他们向疾病控制与预防中心报告近期的非结核分枝杆菌性角膜炎病例。
另外报告了43例角膜炎病例（发病时间在2000年8月至2001年6月之间）。其中，31例是两个不相关的LASIK相关暴发的一部分。其他报告的12例病例为散发性。在后者中，4例与LASIK手术有关。报告的病例均与加利福尼亚州的龟分枝杆菌病例群无关。
非结核分枝杆菌性LASIK相关性角膜炎可能比以前所知的更为常见。
