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Autoradiographic studies on the distribution of 3H-2,3,4-trimethoxy-beta-phenylethylamine in the mouse.

作者信息

Korr H, Seiler N

出版信息

Psychopharmacologia. 1976;46(1):53-8. doi: 10.1007/BF00421549.

DOI:10.1007/BF00421549
PMID:1257367
Abstract

The regional distribution of radioactivity was studied in the brain and in other organs of the mouse by light microscopic autoradiography after injection of 3H-2,3,4-trimethoxy-beta-phenylethylamine (2,3,4,-TMPEA), a nonhallucinogenic isomer of mescaline. The distribution patterns were compared with biochemical and autoradiographic results obtained after 3H-mescaline. Although 2,3,4-TMPEA is rapidly deaminated compared to mescaline its distribution pattern in the brain is similar to that of mescaline at 1 h after injection. However, contrary to mescaline the radioactive labeling becomes more and more homogenously distributed in the brain with tiem. The distribution patterns in kidney, pancreas, adrenal, and spinal ganglia were also different from those observed after application of 3H-mescaline.

摘要

相似文献

1
Autoradiographic studies on the distribution of 3H-2,3,4-trimethoxy-beta-phenylethylamine in the mouse.
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2
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Autoradiographic studies on the distribution of 3H-mescaline in the brain of the marmoset, Callithrix jacchus.狨猴（Callithrix jacchus）大脑中3H-麦司卡林分布的放射自显影研究。
Psychopharmacologia. 1976;46(1):115-7. doi: 10.1007/BF00421558.

本文引用的文献

1
Distribution of carbon-14 labeled isoniazid in brain.碳-14标记异烟肼在脑中的分布。
Neurology. 1957 Dec;7(12):820-4. doi: 10.1212/wnl.7.12.820.
2
Autoradiographic distribution studies in mice with C14-imipramine.用C14-丙咪嗪对小鼠进行放射自显影分布研究。
Int J Neuropsychiatry. 1966 Jun;2(3):269-78.
3
Distribution and fate of C-14-amitriptyline in mice and rats.C-14-阿米替林在小鼠和大鼠体内的分布与转归
Psychopharmacologia. 1965 Jun 1;8(1):1-11. doi: 10.1007/BF00405356.
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Distribution of 35S-chlorpromazine in cat brain.35S-氯丙嗪在猫脑中的分布。
Arch Int Pharmacodyn Ther. 1965 Jul;156(1):48-58.
5
The distribution of 35S-chlorpromazine in mice studied by whole body autoradiography.通过全身放射自显影术研究35S-氯丙嗪在小鼠体内的分布。
Arch Int Pharmacodyn Ther. 1965 Jul;156(1):34-47.
6
Distribution of C-14-labelled amitriptyline in the cat brain.
Psychopharmacologia. 1965 Jun 1;8(1):12-22. doi: 10.1007/BF00405357.
7
LSD: autoradiographic study on the placental transfer and tissue distribution in mice.麦角酸二乙酰胺：小鼠胎盘转运与组织分布的放射自显影研究
Science. 1969 Jun 13;164(3885):1295-7. doi: 10.1126/science.164.3885.1295.
8
Relation of pharmacological and behavioral effects of a hallucinogenic amphetamine to distribution in cat brain.一种致幻性苯丙胺的药理和行为效应与在猫脑内分布的关系。
Science. 1969 May 30;164(3883):1085-6. doi: 10.1126/science.164.3883.1085.
9
Radioautographic study on the distribution of oxypertine (Win 18,501) in mice and cats.氧哌丁苯（Win 18,501）在小鼠和猫体内分布的放射自显影研究。
Psychopharmacologia. 1967;10(5):400-8. doi: 10.1007/BF00403980.
10
Structure-activity relationship studies on mescaline. 3. The influence of the methoxy groups.三甲氧苯乙胺的构效关系研究。3. 甲氧基的影响。
Psychopharmacologia. 1967;10(5):379-87. doi: 10.1007/BF00403978.