一种致幻性苯丙胺的药理和行为效应与在猫脑内分布的关系。
Relation of pharmacological and behavioral effects of a hallucinogenic amphetamine to distribution in cat brain.
作者信息
Idänpään-Heikkilä J E, McIsaac W M, Ho B T, Fritchie G E, Tansey L W
出版信息
Science. 1969 May 30;164(3883):1085-6. doi: 10.1126/science.164.3883.1085.
PMID:5769766
Abstract
The hallucinogen 2,5-dimethoxy,-4-methylamphetamine, also known as STP, accumulates in specfic areas of cat brains. The unchanged compound was detected in the brain for at least 6 hours, whereas its behavioral effects lasted for about 4 hourS. The coincidental pharmacological and behavioral effects of the compound apparently indicate a relation between the anatomical distribution and action.
摘要
致幻剂2,5 - 二甲氧基 - 4 - 甲基苯丙胺，又称STP，在猫脑的特定区域蓄积。在大脑中检测到未变化的该化合物至少持续6小时，而其行为效应持续约4小时。该化合物药理学和行为效应的同时出现显然表明了解剖分布与作用之间的关系。
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