Ando H, Tsuda K
J Autism Child Schizophr. 1975 Sep;5(3):267-74. doi: 10.1007/BF01538156.
A comparative study of developmentally disturbed children as well as normal children is presented with a focus on their position in the family. Demographic data were compared for three groups of Japanese children, with a mean age of 4 years 7 months, who were diagnosed as autistic, cerebral palsied, and trisomic (trisomy 21 mongoloid). The areas compared were maternal age at birth, ratio of males to females, number of siblings, birth order, and age interval between the subject and the closest younger sibling. The normal kindergarten children with a mean age of 4 years 6 months, as well as the Japanese general population, were also compared for these demographic items. The findings on maternal age and sex ratio for these three nosological groups are consistent with recent studies. Although the reproduction of mothers of either cerebral palsied or mongoloid children ceases after the birth of the propositi, the reproduction of mothers of autistic children does not show significant difference from that of normal children's mothers. The age intervals between the subjects and the closest younger sibling do not differ among the three groups or in the normal group.
本文呈现了一项针对发育障碍儿童与正常儿童的比较研究，重点关注他们在家庭中的地位。对三组平均年龄为4岁7个月的日本儿童的人口统计学数据进行了比较，这三组儿童分别被诊断为自闭症、脑瘫和三体综合征（21三体唐氏综合征）。比较的方面包括母亲生育时的年龄、男女比例、兄弟姐妹数量、出生顺序以及受试儿童与最年幼的弟弟或妹妹之间的年龄间隔。还将平均年龄为4岁6个月的正常幼儿园儿童以及日本普通人群的这些人口统计学项目进行了比较。这三个病种组在母亲年龄和性别比例方面的研究结果与近期研究一致。虽然脑瘫儿童或唐氏综合征儿童的母亲在生出先证者后就不再生育，但自闭症儿童的母亲的生育情况与正常儿童的母亲相比并无显著差异。三组儿童以及正常组中，受试儿童与最年幼的弟弟或妹妹之间的年龄间隔并无差异。
