Ashfield James E, Nickel Kyle R, Siemens D Robert, MacNeily Andrew E, Nickel J Curtis
Department of Urology, Queen's University and Kingston General Hospital, Ontario, Canada.
J Urol. 2003 Mar;169(3):1106-8. doi: 10.1097/01.ju.0000048973.26072.eb.
Topical steroids have been advocated as an effective economical alternative to circumcision in boys with phimosis. We evaluated the effectiveness of topical steroid therapy as primary treatment in 194 patients with phimosis.
Between January 1996 and November 2000, 228 boys 16 years old or younger were referred for consideration of circumcision. When intervention was determined to be necessary, a 6-week course of topical steroids was used as primary treatment. Efficacy of treatment was evaluated at 3 months from initiation of therapy.
Of the 228 patients 15 had such a mild degree of phimosis that no intervention was believed to be necessary, 19 were scheduled directly for circumcision due to cosmetic reasons, parent wishes, or severe phimosis with associated voiding problems and the remaining 194 received topical steroids as primary treatment. Of these 194 patients 25 had coexisting balanitis and 4 had a history of urinary tract infection. Conservative treatment was successful in 87%, 88% and 75% of patients with phimosis alone, coexisting balanitis and history of urinary tract infection, respectively. Overall, circumcision was avoided in 87% of patients treated with topical steroids.
Topical steroids are becoming the standard conservative measure for treating phimosis. Our study supports this trend, with an overall efficacy of 87%.
对于患有包茎的男孩,外用类固醇已被提倡作为包皮环切术的一种有效且经济的替代方法。我们评估了外用类固醇疗法作为194例包茎患者主要治疗方法的有效性。
在1996年1月至2000年11月期间,228名16岁及以下的男孩因考虑包皮环切术而前来就诊。当确定有必要进行干预时,采用为期6周的外用类固醇疗程作为主要治疗方法。在治疗开始3个月时评估治疗效果。
在228例患者中,15例包茎程度较轻,认为无需干预;19例因美观原因、家长意愿或伴有排尿问题的严重包茎而直接安排进行包皮环切术;其余194例接受外用类固醇作为主要治疗方法。在这194例患者中,25例合并龟头炎,4例有尿路感染病史。单独患有包茎、合并龟头炎和有尿路感染病史的患者中,保守治疗的成功率分别为87%、88%和75%。总体而言,接受外用类固醇治疗的患者中有87%避免了包皮环切术。
外用类固醇正成为治疗包茎的标准保守措施。我们的研究支持这一趋势,总体有效率为87%。