Liu X, Ling Y, Zheng X, Huang J
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
Yan Ke Xue Bao. 2000 Sep;16(3):163-7.
To investigate the difference of stereometric parameters of optic nerve head between the normal subjects and patients with big-cupped disk and primary open angle glaucoma(POAG).
Twenty-two cases (44 eyes) of normal subjects, 17 cases (34 eyes) of patients with big-cupped disk and 19 cases (37 eyes) of patients with POAG underwent Heidelberg Retina Tomograph (HRT) examination to get topography images and stereometric parameters of optic nerve head.
The stereometric parameters of optic nerve head of the normal, patients with big-cupped disk and POAG were 1) disk area (mm2): 1.995 +/- 0.501, 2.407 +/- 0.661 and 2.248 +/- 0.498; 2) cup area (mm2): 0.573 +/- 0.264, 1.095 +/- 0.673 and 1.340 +/- 0.516; 3) cup/disk ratio: 0.257 +/- 0.095, 0.428 +/- 0.176 and 0.589 +/- 0.195; 4) rim area (mm2): 1.461 +/- 0.328, 1.312 +/- 0.418 and 0.905 +/- 0.409; 5) cup volume (mm3): 0.108 +/- 0.073, 0.347 +/- 0.346 and 0.550 +/- 0.394; 6) rim volume (mm3): 0.421 +/- 0.111, 0.378 +/- 0.225 and 0.224 +/- 0.189; 7) mean cup depth (mm): 0.225 +/- 0.070, 0.327 +/- 0.105 and 0.424 +/- 0.148; 8) maxim cup depth (mm): 0.630 +/- 0.178, 0.732 +/- 0.170 and 0.871 +/- 0.245; 9) cup shape measure (mm): -0.1867 +/- 0.09, -0.108 +/- 0.068 and -0.02 +/- 0.164; 10) mean RNFL thickness (mm): 0.290 +/- 0.053, 0.236 +/- 0.131 and 0.174 +/- 0.134; 11) RNFL cross sectional area (mm2): 1.419 +/- 0.332, 1.263 +/- 0.606 and 0.920 +/- 0.687. Besides, there was no difference of disk area between big cupped disk group and POAG group, no difference of rim area, rim volume and RNFL thickness between normal group and big cupped disk group, statistics analysis showed that there was significant difference of other stereometric parameters between the normal group and big cupped disk group or big cupped disk group and POAG group.
There is certain difference of optic nerve head between the normal subjects and big-cupped disk and patients with POAG.
探讨正常受试者与大杯盘及原发性开角型青光眼(POAG)患者视神经乳头立体测量参数的差异。
对22例(44只眼)正常受试者、17例(34只眼)大杯盘患者和19例(37只眼)POAG患者进行海德堡视网膜断层扫描(HRT)检查,以获取视神经乳头的地形图图像和立体测量参数。
正常受试者、大杯盘患者和POAG患者视神经乳头的立体测量参数如下:1)视盘面积(mm²):1.995±0.501、2.407±0.661和2.248±0.498;2)杯盘面积(mm²):0.573±0.264、1.095±0.673和1.340±0.516;3)杯盘比:0.257±0.095、0.428±0.176和0.589±0.195;4)视盘边缘面积(mm²):1.461±0.328、1.312±0.418和0.905±0.409;5)杯盘容积(mm³):0.108±0.073、0.347±0.346和0.550±0.394;6)视盘边缘容积(mm³):0.421±0.111、0.378±0.225和0.224±0.189;7)平均杯盘深度(mm):0.225±0.070、0.327±0.105和0.424±0.148;8)最大杯盘深度(mm):0.630±0.178、0.732±0.170和0.871±0.245;9)杯盘形状测量值(mm):-0.1867±0.09、-0.108±0.068和-0.02±0.164;10)平均视网膜神经纤维层(RNFL)厚度(mm):0.290±0.053、0.236±0.131和0.174±0.134;11)RNFL横截面积(mm²):1.419±0.332、1.263±0.606和0.920±0.687。此外,大杯盘组与POAG组之间视盘面积无差异,正常组与大杯盘组之间视盘边缘面积、视盘边缘容积和RNFL厚度无差异,统计学分析显示正常组与大杯盘组或大杯盘组与POAG组之间其他立体测量参数存在显著差异。
正常受试者与大杯盘及POAG患者的视神经乳头存在一定差异。