Kobelt G, Borgström F, Mattiasson A
HDI France, 492 Chemin des Laurens, 06530 Spéracèdes, France.
BJU Int. 2003 Feb;91(3):190-5. doi: 10.1046/j.1464-410x.2003.04062.x.
To assess the effect of nocturia on productivity, vitality and utility in a selected group of professionally active individuals with nocturia, compared with matched controls, and investigate the effect of symptom severity, to test the hypothesis that lack of sleep caused by frequent sleep interruptions could reduce an individuals' daytime energy and activity levels.
Subjects (203) were recruited in Sweden through advertisements, and their suitability for the study assessed in a structured interview. Controls (80) matched for age and gender were randomly selected from a market research panel and given the same interview. Both groups completed a productivity questionnaire, a generic quality-of-life questionnaire with a specific domain for vitality and a utility instrument.
The study group with nocturia had a significantly lower level of vitality and utility, and greater impairment of work and activity, than the control group. Women were more affected than men. Symptom severity correlated with all three measures.
In an otherwise healthy and professionally active group of individuals, waking at night to void significantly diminishes their overall well-being, vitality and productivity, leading to a significant level of indirect and intangible costs.
在一组有夜尿症的职业活跃个体中,与匹配的对照组相比,评估夜尿症对生产力、活力和效用的影响,并研究症状严重程度的影响,以检验频繁睡眠中断导致的睡眠不足会降低个体白天能量和活动水平这一假设。
通过广告在瑞典招募了203名受试者,并在结构化访谈中评估他们参与研究的适宜性。从市场研究小组中随机挑选了80名年龄和性别匹配的对照组,并进行相同的访谈。两组均完成了一份生产力问卷、一份具有活力特定领域的通用生活质量问卷以及一份效用工具。
有夜尿症的研究组与对照组相比,活力和效用水平显著更低,工作和活动受到的损害更大。女性比男性受影响更大。症状严重程度与所有三项指标均相关。
在一组原本健康且职业活跃的个体中,夜间醒来排尿会显著降低他们的整体幸福感、活力和生产力,导致相当程度的间接和无形成本。