Sağ Sinem, Nas Kemal, Sağ Mustafa Serdar, Tekeoğlu İbrahim, Kamanlı Ayhan
J Back Musculoskelet Rehabil. 2018;31(3):499-505. doi: 10.3233/BMR-169657.
In this study, our objective was to determine the work productivity and work disability of the patients with ankylosing spondylitis (AS) and to investigate the relation of these parameters with disease activity, anxiety, depression and quality of life.
Fifty patients with the diagnosis of AS and 30 healthy control were included in the study. In patients with AS, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) was used to evaluate the disease activity; Bath Ankylosing Spondylitis Metrology Index (BASMI) was used to evaluate the spinal mobility and Bath Ankylosing Spondylitis Functional Index (BASFI) was used to determine the functional status. In addition, the Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire and The Short Form (SF-36) Health Survey was used to evaluate the health status, Hospital Anxiety and Depression Scale (HADS) was used for the evaluation of depression and anxiety and Work Productivity and Activity Impairment Questionnaire: Specific Health Problem v2.0 (WPAI:SHP) was used to evaluate the work productivity.
In AS patients duration of disease at the diagnosis was 7.24 ± 6.23 years. The time lost at work due to the disease, decrease in the work productivity and impairment in the time off daily activities were worse in the patient group compared with the control group (p< 0.05). The impairment in the work productivity was correlated with BASDAI and depression; difficulty in time-off activities was correlated with BASFI and anxiety and depression was correlated with BASDAI (p< 0.05). While the impairment in work productivity was correlated with the subparameter vitality in SF-36, difficulty in time off activities was correlated with general health status, social functions, vitality and mental health (p< 0.05).
In this study, we determined that AS had a significant influence on the working conditions and the factors related to the disease had a significant correlation with work productivity. Factors related to the psychology and the disease were also correlated with the working conditions.
在本研究中,我们的目的是确定强直性脊柱炎(AS)患者的工作效率和工作能力丧失情况,并研究这些参数与疾病活动度、焦虑、抑郁和生活质量之间的关系。
本研究纳入了50例诊断为AS的患者和30名健康对照者。对于AS患者,采用巴斯强直性脊柱炎疾病活动指数(BASDAI)评估疾病活动度;采用巴斯强直性脊柱炎测量指数(BASMI)评估脊柱活动度,采用巴斯强直性脊柱炎功能指数(BASFI)确定功能状态。此外,使用强直性脊柱炎生活质量(ASQoL)问卷和简短健康调查问卷(SF-36)评估健康状况,使用医院焦虑抑郁量表(HADS)评估抑郁和焦虑,使用工作效率与活动障碍问卷:特定健康问题v2.0(WPAI:SHP)评估工作效率。
AS患者诊断时的病程为7.24±6.23年。与对照组相比,患者组因疾病导致的工作时间损失、工作效率下降和日常活动时间的损伤更严重(p<0.05)。工作效率损伤与BASDAI和抑郁相关;日常活动困难与BASFI、焦虑相关,抑郁与BASDAI相关(p<0.05)。工作效率损伤与SF-36中的子参数活力相关,日常活动困难与总体健康状况、社会功能、活力和心理健康相关(p<0.05)。
在本研究中,我们确定AS对工作条件有显著影响,与疾病相关的因素与工作效率有显著相关性。与心理和疾病相关的因素也与工作条件相关。