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夏季纯母乳喂养婴儿及其母亲的维生素D缺乏和不足:对母乳喂养婴儿补充维生素D的合理性说明

Hypovitaminosis D and vitamin D deficiency in exclusively breast-feeding infants and their mothers in summer: a justification for vitamin D supplementation of breast-feeding infants.

作者信息

Dawodu Adekunle, Agarwal Mukesh, Hossain Moshaddeque, Kochiyil Jose, Zayed Reem

机构信息

Department of Paediatrics, Faculty of Medicine and Health Sciences, UAE University, United Arab Emirates.

出版信息

J Pediatr. 2003 Feb;142(2):169-73. doi: 10.1067/mpd.2003.63.


DOI:10.1067/mpd.2003.63
PMID:12584539
Abstract

OBJECTIVE: To determine the prevalence of hypovitaminosis D in exclusively breast-feeding infants and their mothers in a community where maternal sunshine exposure is low. STUDY DESIGN: Serum levels of calcium, phosphate, alkaline phosphatase, 25-hydroxy vitamin D (25-OHD), and intact parathyroid hormone were measured in 90 unsupplemented healthy term breast-feeding Arab/South Asian infants and their mothers in summer. Maternal dietary vitamin D intake was also estimated. RESULTS: The median age of infants was 6 weeks. The median serum 25-OHD concentrations in mothers (8.6 ng/mL) and infants (4.6 ng/mL) were low, and 61% of the mothers and 82% of the 78 infants tested had hypovitaminosis D (serum 25-OHD <10 ng/mL). The infants with hypovitaminosis D had elevated serum alkaline phosphatase and a tendency to higher serum intact parathyroid hormone levels. The average daily maternal vitamin D intake from commercial milk was 88 IU. CONCLUSIONS: Hypovitaminosis D is common in summer in exclusively breast-feeding infants and their mothers. The results provide justification for vitamin D supplementation of breast-feeding infants and mothers in the United Arab Emirates. Low vitamin D intake probably contributed to low maternal vitamin D status.

摘要

目的:在一个母亲日照较少的社区,确定纯母乳喂养婴儿及其母亲维生素D缺乏症的患病率。 研究设计:在夏季,对90名未补充维生素D的健康足月纯母乳喂养的阿拉伯/南亚婴儿及其母亲测量血清钙、磷、碱性磷酸酶、25-羟基维生素D(25-OHD)和完整甲状旁腺激素水平。同时估算母亲膳食中维生素D的摄入量。 结果:婴儿的中位年龄为6周。母亲(8.6 ng/mL)和婴儿(4.6 ng/mL)血清25-OHD浓度中位数较低,61%的母亲和接受检测的78名婴儿中的82%患有维生素D缺乏症(血清25-OHD<10 ng/mL)。患有维生素D缺乏症的婴儿血清碱性磷酸酶升高,血清完整甲状旁腺激素水平有升高趋势。母亲从商业牛奶中每日摄入维生素D的平均量为88 IU。 结论:纯母乳喂养婴儿及其母亲在夏季维生素D缺乏症很常见。研究结果为阿拉伯联合酋长国的母乳喂养婴儿和母亲补充维生素D提供了依据。维生素D摄入量低可能导致母亲维生素D水平低下。

相似文献

[1]
Hypovitaminosis D and vitamin D deficiency in exclusively breast-feeding infants and their mothers in summer: a justification for vitamin D supplementation of breast-feeding infants.

J Pediatr. 2003-2

[2]
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[3]
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[4]
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[6]
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Eur J Clin Nutr. 2002-5

[8]
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[10]
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引用本文的文献

[1]
Vitamin D status among apparently healthy individuals in the UAE: a systematic review.

Front Nutr. 2025-7-9

[2]
Prevalence of vitamin D deficiency in exclusively breastfed infants at Charoenkrung Pracharak Hospital.

World J Clin Pediatr. 2024-3-9

[3]
Nutritional Status of Breastfeeding Mothers and Impact of Diet and Dietary Supplementation: A Narrative Review.

Nutrients. 2024-1-19

[4]
Prevalence of hypovitaminosis D among children and adolescents of Kabul: a descriptive cross-sectional study.

BMC Pediatr. 2023-2-1

[5]
Maternal vitamin D and growth of under-five children: a systematic review and meta-analysis of observational and interventional studies.

Glob Health Action. 2022-12-31

[6]
Risk factors for vitamin D deficiency in Abu Dhabi Emirati population.

PLoS One. 2022

[7]
Factors Influencing Vitamin D Levels in Neonatal Umbilical Cord Blood: A Two-Center Study From Tibet and Shenyang.

Front Pediatr. 2020-11-23

[8]
Vitamin D supplementation for term breastfed infants to prevent vitamin D deficiency and improve bone health.

Cochrane Database Syst Rev. 2020-12-11

[9]
Prenatal vitamin D supplementation and child respiratory health: A systematic review and meta-analysis of randomized controlled trials.

World Allergy Organ J. 2020-11-21

[10]
The prevalence and determinants of vitamin D deficiency in Indonesian infants at birth and six months of age.

PLoS One. 2020-10-5

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