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门静脉血流的手术恢复可纠正与肝外门静脉血栓形成相关的促凝和抗凝缺陷。

Surgical restoration of portal flow corrects procoagulant and anticoagulant deficiencies associated with extrahepatic portal vein thrombosis.

作者信息

Mack Cara L, Superina Riccardo A, Whitington Peter F

机构信息

Departments of Pediatrics and Surgery, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois 60614, USA.

出版信息

J Pediatr. 2003 Feb;142(2):197-9. doi: 10.1067/mpd.2003.93.

Abstract

Extrahepatic portal vein thrombosis (EHPVT) is associated with abnormal circulating procoagulants and anticoagulants. Eleven children with EHPVT and abnormal coagulation factors underwent a mesenterico-left portal vein bypass to restore portal flow. Coagulation factors had returned to normal by one year. The data suggest that portal venous flow is essential for maintaining normal coagulation.

摘要

肝外门静脉血栓形成(EHPVT)与循环中促凝血剂和抗凝剂异常有关。11名患有EHPVT且凝血因子异常的儿童接受了肠系膜-左门静脉搭桥术以恢复门静脉血流。凝血因子在1年内恢复正常。数据表明门静脉血流对于维持正常凝血至关重要。

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