Pichler M, Kleinberger G, Kotzaurek R, Pall H, Szeless S
Wien Klin Wochenschr. 1976 Jan 23;88(2):72-4.
Dopamine possesses specific pharmacological actions which distinguish it from the other catecholamines. Apart from its positive inotropic effect, dopamine exerts a favourable influence on renal function with an increase in renal blood flow and alterations in intrarenal haemodynamics. The use of dopamine in the early stages of acute oliguric failure is recommended on the basis of the good therapeutic response achieved in a series of cases.
多巴胺具有特定的药理作用,使其有别于其他儿茶酚胺。除了其正性肌力作用外,多巴胺还对肾功能产生有利影响,可增加肾血流量并改变肾内血流动力学。基于一系列病例取得的良好治疗效果,建议在急性少尿性肾衰竭的早期使用多巴胺。