多巴胺与间羟异丙肾上腺素对猫心室颤动阈值影响的比较研究
A comparative study on the influence of dopamine and metaproterenol on the ventricular fibrillation threshold in cats.
作者信息
Marquardt R, Fischer J, Küstner W
出版信息
Basic Res Cardiol. 1977 Jul-Aug;72(4):376-82. doi: 10.1007/BF02023596.
PMID:901379
Abstract
The influence of 3-4-dihydroxyphenylethylamine (dopamine) on the VFT of the cat heart was checked with different doses in comparison to metaproterenol (Alupent). In the therapeutical doses dopamine has no significant influence on the VFT in contrast to metaproterenol. The clinical relevance of our findings seems to be that dopamine can be applied in therapeutical doses without running the risk of inducing serious cardiac arrhythmia.
摘要
将3-4-二羟基苯乙胺（多巴胺）与间羟异丙肾上腺素（喘速宁）相比较，以不同剂量检查其对猫心脏心室颤动阈值（VFT）的影响。与间羟异丙肾上腺素相比，治疗剂量的多巴胺对心室颤动阈值没有显著影响。我们研究结果的临床意义似乎在于，多巴胺可以以治疗剂量应用，而不会有诱发严重心律失常的风险。
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