Ghosh Anil, Srinivasan Prakash, Abraham Eappen G, Fujioka Hisashi, Jacobs-Lorena Marcelo
Case Western Reserve University, Department of Genetics, 10900 Euclid Avenue, Cleveland, Ohio 44106-4955, USA.
Trends Parasitol. 2003 Feb;19(2):94-101. doi: 10.1016/s1471-4922(02)00052-1.
It is widely known that malaria kills millions of people every year. Less well recognized is the fact that the situation is steadily deteriorating for a lack of effective means to counter the disease. An essential first step towards the development of new approaches to fight malaria is a thorough understanding of the mechanisms that direct parasite growth and differentiation, including parasite-host interactions. This article reviews recent achievements and introduces some promising new technologies and approaches for studying host-parasite interactions.
众所周知，疟疾每年导致数百万人死亡。但鲜为人知的是，由于缺乏有效的对抗该疾病的手段，情况正在稳步恶化。开发对抗疟疾新方法的关键的第一步是全面了解指导寄生虫生长和分化的机制，包括寄生虫与宿主的相互作用。本文回顾了近期的成果，并介绍了一些用于研究宿主-寄生虫相互作用的有前景的新技术和方法。
