Szepietowski Jacek C, Reich Adam, Wiśnicka Beata
Department of Dermatology and Venereology, University of Medicine, Ul. Chalubinskiego 1, 35-368 Wrocław, Poland.
Acta Dermatovenerol Croat. 2002 Dec;10(4):221-6.
Some psoriatic patients suffer from intensive itching, however, literature data on its prevalence and especially on clinical manifestation are very limited. This study was undertaken to evaluate the frequency and clinical characteristics of itching in patients with psoriasis and to correlate the presence and intensity of pruritus with clinical severity of psoriasis. One hundred psoriatic individuals (psoriasis vulgaris in 77% and arthropatic psoriasis in 23%) were included in the study. The severity of psoriasis was assessed according to PASI score. Itching was evaluated using two methods: visual analog scale (VAS) and a specially designed questionnaire method. Itching was found in 80% of psoriatic patients. The severity of psoriasis in pruritic patients was significantly (p<0.004) higher as compared to non-pruritic subjects. Significant correlations were found between PASI scores and intensity of itching, as assessed by both scales: VAS and the questionnaire method (r=0.29, p<0.01 for both analyses). The presence and intensity of itching did not depend on age and gender of patients, type of psoriasis, duration of disease, and last outbreak of psoriasis. Generalized itching was reported by 28.7% of pruritic patients. The most common sites of itching were lower limbs (50%), trunk (48.7%), upper limbs (48.7%) and scalp (35%). Face appeared to be the least commonly affected skin area by itching (only 1.2%). We conclude that itching is a common symptom in patients with psoriasis, and its intensity correlates with clinical severity of the disease.
一些银屑病患者会遭受剧烈瘙痒，然而，关于其患病率尤其是临床表现的文献资料非常有限。本研究旨在评估银屑病患者瘙痒的频率和临床特征，并将瘙痒的存在及强度与银屑病的临床严重程度相关联。该研究纳入了100名银屑病患者（寻常型银屑病占77%，关节病型银屑病占23%）。根据银屑病面积和严重程度指数（PASI）评分评估银屑病的严重程度。使用两种方法评估瘙痒：视觉模拟量表（VAS）和一种专门设计的问卷调查方法。在80%的银屑病患者中发现了瘙痒。与无瘙痒的受试者相比，瘙痒患者的银屑病严重程度显著更高（p<0.004）。通过VAS和问卷调查这两种量表评估发现，PASI评分与瘙痒强度之间存在显著相关性（两种分析的r均为0.29，p<0.01）。瘙痒的存在及强度不取决于患者的年龄、性别、银屑病类型、病程以及银屑病的上次发作情况。28.7%的瘙痒患者报告有全身性瘙痒。最常见的瘙痒部位是下肢（50%）、躯干（48.7%）、上肢（48.7%）和头皮（35%）。面部似乎是瘙痒最少累及的皮肤区域（仅1.2%）。我们得出结论，瘙痒是银屑病患者的常见症状，其强度与疾病的临床严重程度相关。
