Department of Dermatology, Venereology and Allergology, Wroc av Medical University, 50-368 Wroclaw, Poland.
Acta Derm Venereol. 2010 May;90(3):257-63. doi: 10.2340/00015555-0851.
The aim of this study was to evaluate the relationship between itch and the well-being of patients with psoriasis. In a study of 102 patients with plaque-type psoriasis, pruritus was found in 91 (89.2%) patients during exacerbation of psoriasis. No significant correlation was found between disease severity and the presence and intensity of pruritus. However, pruritus intensity correlated significantly with patients' quality of life, feelings of stigmatization, stress experienced within a period of one month before psoriasis outbreak, and depressive symptoms. In conclusion, pruritus may have a significant negative influence on the psychosocial status of patients with psoriasis. There is a need for the development of effective anti-pruritic treatments in order to improve the well-being of patients with psoriasis.
本研究旨在评估瘙痒与银屑病患者福祉之间的关系。在一项针对 102 例斑块状银屑病患者的研究中,发现 91 例(89.2%)患者在银屑病恶化期间出现瘙痒。未发现疾病严重程度与瘙痒的存在和强度之间存在显著相关性。然而,瘙痒强度与患者的生活质量、污名感、银屑病发作前一个月内的压力和抑郁症状显著相关。总之,瘙痒可能对银屑病患者的社会心理状态产生重大负面影响。需要开发有效的止痒治疗方法,以改善银屑病患者的福祉。