Nicholas R A J, Ayling R D
Mycoplasma Group, Department of Bacterial Diseases, Veterinary Laboratories Agency (Weybridge), Addlestone, Surrey KT15 3NB, UK.
Res Vet Sci. 2003 Apr;74(2):105-12. doi: 10.1016/s0034-5288(02)00155-8.
Mycoplasma bovis is a major, but often overlooked, pathogen causing respiratory disease, mastitis, and arthritis in cattle. It is found worldwide and has spread into new areas, including Ireland and parts of South America, in the last decade. In Europe, it is responsible for at least a quarter to a third of all calf pneumonia although this may be an underestimate as few laboratories regularly monitor for mycoplasmas. Like all mollicutes, M. bovis is inherently refractory to certain groups of antibiotics because it does not possess a cell wall; furthermore evidence is accumulating that strains of M. bovis are becoming resistant to antibiotics, including tetracycline, tilmicosin and spectinomycin, traditionally used for their control. No vaccines are presently available for the control of M. bovis infections.
牛支原体是一种主要但常被忽视的病原体，可导致牛的呼吸道疾病、乳腺炎和关节炎。它在全球范围内都有发现，并且在过去十年中已传播到新的地区，包括爱尔兰和南美洲部分地区。在欧洲，它至少导致了四分之一至三分之一的犊牛肺炎，不过这可能是低估了，因为很少有实验室定期监测支原体。与所有柔膜菌纲细菌一样，牛支原体天生对某些抗生素类别具有耐药性，因为它没有细胞壁；此外，越来越多的证据表明，牛支原体菌株对传统上用于控制其感染的抗生素（包括四环素、替米考星和壮观霉素）产生了耐药性。目前尚无用于控制牛支原体感染的疫苗。
