El Manira Abdeljabbar, Kettunen Petronella, Hess Dietmar, Krieger Patrik
Department of Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.
Brain Res Brain Res Rev. 2002 Oct;40(1-3):9-18. doi: 10.1016/s0165-0173(02)00184-4.
Spinal networks generate the motor pattern underlying locomotion. These are subject to modulatory systems that influence their operation and thereby result in a flexible network organization. In this review, we have summarized the mechanisms by which the different metabotropic glutamate receptor subtypes fine-tune the cellular and synaptic properties and thus underlie intrinsic modulation of the activity of the locomotor network in the lamprey.
脊髓网络产生运动的基础运动模式。这些网络受到调节系统的影响，调节系统会影响其运作，从而形成灵活的网络组织。在这篇综述中，我们总结了不同代谢型谷氨酸受体亚型微调细胞和突触特性的机制，这些机制构成了七鳃鳗运动网络活动内在调节的基础。
