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[科特迪瓦四种疟疾诊断技术的比较研究]

[Comparative study of four malaria diagnostic techniques used in Ivory Coast].

作者信息

Yavo W, Ackra K N, Menan E I H, Barro-Kiki P C, Kassi R R, Adjetey T A K, Bamba A, Kone M

机构信息

Laboratoire de parasitologie-mycologie de l'Institut Pasteur de Côte d'Ivoire, UFR des sciences pharmaceutiques et biologiques d'Abidjan, Abidjan, République de Côte d'Ivoire.

出版信息

Bull Soc Pathol Exot. 2002 Nov;95(4):238-40.

PMID:12596367
Abstract

The biological diagnosis of malaria plays an important part in the patients' treatment for malaria. Thus, many techniques have been developed to reach this purpose. We have compared four of them concerning 196 patients from October, 1996 to January, 1997 in Abidjan. Thick blood film has been chosen as the technique for reference. It has come out that the plasmodic index was 18.3%. The Plasmodium falciparum has been the only encountered species. The different sensitivities of the QBC test and of the Parasight F test reached 100% against 83.3% in the case of the thin blood film. The QBC test and the thin blood film had each a specificity of 100% against 88.1% for the Parasight F test. Unlike the QBC test, the thick blood film and the thin blood film have remained the most difficult to be realised. Therefore, the analysis of parameters of credibility (sensitivity, specificity), predictable values and the time involved will allow in a given situation to use the appropriate biological diagnosis technique.

摘要

疟疾的生物学诊断在疟疾患者的治疗中起着重要作用。因此,已经开发了许多技术来实现这一目的。1996年10月至1997年1月期间,我们在阿比让对196名患者的四种技术进行了比较。厚血膜已被选为参考技术。结果显示疟原虫指数为18.3%。恶性疟原虫是唯一发现的种类。QBC检测和Parasight F检测的不同敏感性分别达到100%,而薄血膜检测的敏感性为83.3%。QBC检测和薄血膜检测的特异性均为100%,而Parasight F检测的特异性为88.1%。与QBC检测不同,厚血膜和薄血膜仍然是最难实现的。因此,对可信度参数(敏感性、特异性)、预测值和所涉及的时间进行分析,将有助于在特定情况下使用适当的生物学诊断技术。

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